ID   A0A1Y3B2H9_EURMA        Unreviewed;       289 AA.
AC   A0A1Y3B2H9;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Group 1 mite allergen-like protein (Cysteine protease) {ECO:0000313|EMBL:OTF74254.1};
GN   ORFNames=BLA29_007497 {ECO:0000313|EMBL:OTF74254.1};
OS   Euroglyphus maynei (Mayne's house dust mite).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Acariformes; Sarcoptiformes; Astigmata; Psoroptidia; Analgoidea;
OC   Pyroglyphidae; Pyroglyphinae; Euroglyphus.
OX   NCBI_TaxID=6958 {ECO:0000313|EMBL:OTF74254.1, ECO:0000313|Proteomes:UP000194236};
RN   [1] {ECO:0000313|EMBL:OTF74254.1, ECO:0000313|Proteomes:UP000194236}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Arlian Lab {ECO:0000313|EMBL:OTF74254.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:OTF74254.1};
RA   Arlian L.G., Morgan M.S., Rider S.D.;
RT   "Genome Survey of Euroglyphus maynei.";
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase C1 family.
CC       {ECO:0000256|ARBA:ARBA00008455}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OTF74254.1}.
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DR   EMBL; MUJZ01047946; OTF74254.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y3B2H9; -.
DR   OrthoDB; 808912at2759; -.
DR   Proteomes; UP000194236; Unassembled WGS sequence.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd02620; Peptidase_C1A_CathepsinB; 1.
DR   Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR013128; Peptidase_C1A.
DR   InterPro; IPR000668; Peptidase_C1A_C.
DR   PANTHER; PTHR12411:SF895; CATHEPSIN B; 1.
DR   PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR   Pfam; PF00112; Peptidase_C1; 1.
DR   SMART; SM00645; Pept_C1; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000313|EMBL:OTF74254.1};
KW   Protease {ECO:0000313|EMBL:OTF74254.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000194236}.
FT   DOMAIN          35..286
FT                   /note="Peptidase C1A papain C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00645"
SQ   SEQUENCE   289 AA;  33250 MW;  9922ADAE27D0A362 CRC64;
     MGKNLKCLNG AIEETVEQYQ PEKRNQRQFI IDDYLPDFFD AREKWPNCRT ISLIPNQGQY
     CSSCWAVGVV QTINDRICIG SNQRINVEIS AQDLLTCCKE CTNDGEGCHG GYPSRGWNYW
     VTNGLVTGGQ YGDHNTCQPF NIPPMNLATF IPYRQSSHIM QTPVCQQQCV NGKDYFQDKY
     YGLHYYKLPN DERKIREEIF HHGPVEANYR VYPDFHHYKT GVYQHLRGSE SEGHSIKIIG
     WGIENGLPYW LCANSWTPLW GGMGGFFKIL RGQNHCGIEN QVYGGWPRV
//