ID A0A1Y3BUA8_EURMA Unreviewed; 444 AA.
AC A0A1Y3BUA8;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 22-FEB-2023, entry version 15.
DE SubName: Full=Phosphatidylinositol 3-kinase regulatory subunit alpha-like protein {ECO:0000313|EMBL:OTF83568.1};
DE Flags: Fragment;
GN ORFNames=BLA29_005131 {ECO:0000313|EMBL:OTF83568.1};
OS Euroglyphus maynei (Mayne's house dust mite).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Sarcoptiformes; Astigmata; Psoroptidia; Analgoidea;
OC Pyroglyphidae; Pyroglyphinae; Euroglyphus.
OX NCBI_TaxID=6958 {ECO:0000313|EMBL:OTF83568.1, ECO:0000313|Proteomes:UP000194236};
RN [1] {ECO:0000313|EMBL:OTF83568.1, ECO:0000313|Proteomes:UP000194236}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Arlian Lab {ECO:0000313|EMBL:OTF83568.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:OTF83568.1};
RA Arlian L.G., Morgan M.S., Rider S.D.;
RT "Genome Survey of Euroglyphus maynei.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OTF83568.1}.
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DR EMBL; MUJZ01003167; OTF83568.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y3BUA8; -.
DR OrthoDB; 2880119at2759; -.
DR Proteomes; UP000194236; Unassembled WGS sequence.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 2.
DR InterPro; IPR032498; PI3K_P85_iSH2.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR PANTHER; PTHR10155; PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR10155:SF10; PI3K21B, ISOFORM B; 1.
DR Pfam; PF16454; PI3K_P85_iSH2; 1.
DR Pfam; PF00017; SH2; 2.
DR PRINTS; PR00678; PI3KINASEP85.
DR PRINTS; PR00401; SH2DOMAIN.
DR SMART; SM00252; SH2; 2.
DR SUPFAM; SSF55550; SH2 domain; 2.
DR PROSITE; PS50001; SH2; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:OTF83568.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000194236};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191};
KW Transferase {ECO:0000313|EMBL:OTF83568.1}.
FT DOMAIN 87..182
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT DOMAIN 351..444
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT REGION 1..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 196..230
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..73
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 444
FT /evidence="ECO:0000313|EMBL:OTF83568.1"
SQ SEQUENCE 444 AA; 51904 MW; 16B02210D94E1BD8 CRC64;
MTTEEEKQEQ SSSTSTATTA TTTTTITTEQ SITDNTNEQC ENDSQQPQQL SLQQQQPPLE
SSTSSLEQNV QQQQPEMEEE RLEDAEWYWG KISRKEVNEK LRNRPDGTFL VRDSISKVFG
EYTLTLRKNN TNKLIKITSH DGLYGFSVPF VFKSVVELIN YYKNESLAKY NPSLDVKLLY
PVSRFQQPPD IEGIEINDME KVKARLAEVR KELKTKNQQY DQLSEDYDKN SKCIQRQRQA
IRSYQLIMGF IQDHINLNNK LQVQALPHEA NLMQEQKIKL QNRLNFFNKS IGDLENDLKL
MIAYNRLLDR ERNSIKPTLQ FLGRQHNILH KIVEQNTDEI DLQPHKIETT WLINECKRHE
AEQLLKNKKD GTFLIRQSRQ QMGKYALSIV SDGIVYHCLI SKTERGYGFS EPYDIFPDLM
SLVLHYSKTS LEEHNDNLHT TLRY
//
