ID A0A1Y3G5L8_9PROT Unreviewed; 343 AA.
AC A0A1Y3G5L8;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 12.
DE SubName: Full=Isocitrate dehydrogenase {ECO:0000313|EMBL:OUI88768.1};
DE EC=1.1.1.41 {ECO:0000313|EMBL:OUI88768.1};
GN ORFNames=HK11_03580 {ECO:0000313|EMBL:OUI88768.1};
OS Acetobacter sp. DmW_043.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Acetobacter.
OX NCBI_TaxID=1670658 {ECO:0000313|EMBL:OUI88768.1, ECO:0000313|Proteomes:UP000196359};
RN [1] {ECO:0000313|EMBL:OUI88768.1, ECO:0000313|Proteomes:UP000196359}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DmW_043 {ECO:0000313|EMBL:OUI88768.1,
RC ECO:0000313|Proteomes:UP000196359};
RA Ju J., Zhang J.;
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the isocitrate and isopropylmalate
CC dehydrogenases family. {ECO:0000256|ARBA:ARBA00007769}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUI88768.1}.
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DR EMBL; JOMN01000013; OUI88768.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y3G5L8; -.
DR OrthoDB; 9767905at2; -.
DR Proteomes; UP000196359; Unassembled WGS sequence.
DR GO; GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR InterPro; IPR019818; IsoCit/isopropylmalate_DH_CS.
DR InterPro; IPR024084; IsoPropMal-DH-like_dom.
DR PANTHER; PTHR11835; DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE; 1.
DR PANTHER; PTHR11835:SF34; ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR Pfam; PF00180; Iso_dh; 1.
DR SMART; SM01329; Iso_dh; 1.
DR SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
DR PROSITE; PS00470; IDH_IMDH; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:OUI88768.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000196359}.
FT DOMAIN 7..338
FT /note="Isopropylmalate dehydrogenase-like"
FT /evidence="ECO:0000259|SMART:SM01329"
SQ SEQUENCE 343 AA; 36919 MW; 0E3F70F4BDB604B4 CRC64;
MTKDSKTIPA TLIPGDGIGP EIMDSVVEIL DTVGAPFVWD KQLAGMAGVD AVNDPLPKQT
IESIRRTSLA LKGPLTTPVG GGFKSINVTM RQEFGLFANM RPTKTIIPGG RYEDIDFVMF
RENLEGYYAA MEHYVPVGDD PKGIALSTGY NSRAECRRIV KFAFDYAVAN NRKTVTLVHK
ANILKLLTGI FLEEGRKVAE EYKGRVEFND RIVDACAMQL VTNPWQFDVI VTTNLFGDIL
SDLASGLIGG LGMAPGANIG EKAAVFEAVH GSAPDIAGKG LANPLALLMA AVMMLQHVGR
QDLADRINHG IKKTITEGGI RTKDLGGNAT TKDLTAALKQ QLS
//
