ID A0A1Y3G869_9PROT Unreviewed; 296 AA.
AC A0A1Y3G869;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=HTH-type transcriptional regulator MetR {ECO:0000256|ARBA:ARBA00019365};
GN ORFNames=HK11_03405 {ECO:0000313|EMBL:OUI89727.1};
OS Acetobacter sp. DmW_043.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Acetobacter.
OX NCBI_TaxID=1670658 {ECO:0000313|EMBL:OUI89727.1, ECO:0000313|Proteomes:UP000196359};
RN [1] {ECO:0000313|EMBL:OUI89727.1, ECO:0000313|Proteomes:UP000196359}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DmW_043 {ECO:0000313|EMBL:OUI89727.1,
RC ECO:0000313|Proteomes:UP000196359};
RA Ju J., Zhang J.;
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUI89727.1}.
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DR EMBL; JOMN01000001; OUI89727.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y3G869; -.
DR OrthoDB; 155872at2; -.
DR Proteomes; UP000196359; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd08441; PBP2_MetR; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR037406; MetR_PBP2.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30126; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR PANTHER; PTHR30126:SF25; HTH-TYPE TRANSCRIPTIONAL REGULATOR METR; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Methionine biosynthesis {ECO:0000256|ARBA:ARBA00023167};
KW Reference proteome {ECO:0000313|Proteomes:UP000196359};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..61
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 296 AA; 33589 MW; F7842D381BBE6FAB CRC64;
MDVLERSHLK VIQAVAREGS LTAAGLRLNL TQPALSHAIR KIENQLGVKV WRREGRSLVL
TQAGEWLLSL ANRMLPQFEL AEKRLEQFGN GERGTLRIGM ECHPCYQWLL KVVSPYLERW
PKVDVDVRQK FQFGGIGALF SNEIDLVVTP DPLYKPGLKF TPVFDYELVL VVGPQHPLRG
EKFISPEQLA GETLITYPVP SERLDIYTQF LQPAGISPRQ QKQIETTDIM LVMVAHGRGV
TALPGWLVEE YAQRFELSPV KLGKKGIAKQ IFLGCRDTDD DIFYLQDFIR FAASHH
//
