ID   A0A1Y3GB49_9EURY        Unreviewed;       741 AA.
AC   A0A1Y3GB49;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Amino acid transporter fused to UspA-like domain {ECO:0000313|EMBL:OUJ18648.1};
GN   ORFNames=AMET1_0294 {ECO:0000313|EMBL:OUJ18648.1};
OS   Methanonatronarchaeum thermophilum.
OC   Archaea; Euryarchaeota; Methanonatronarchaeia; Methanonatronarchaeales;
OC   Methanonatronarchaeaceae; Methanonatronarchaeum.
OX   NCBI_TaxID=1927129 {ECO:0000313|EMBL:OUJ18648.1, ECO:0000313|Proteomes:UP000195137};
RN   [1] {ECO:0000313|EMBL:OUJ18648.1, ECO:0000313|Proteomes:UP000195137}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AMET1 {ECO:0000313|EMBL:OUJ18648.1};
RA   Sorokin D.Y., Makarova K.S., Abbas B., Ferrer M., Golyshin P.N.;
RT   "Discovery of methanogenic haloarchaea.";
RL   Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUJ18648.1}.
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DR   EMBL; MRZU01000003; OUJ18648.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y3GB49; -.
DR   Proteomes; UP000195137; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd00293; USP_Like; 1.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   Gene3D; 3.40.50.620; HUPs; 2.
DR   InterPro; IPR002293; AA/rel_permease1.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR006016; UspA.
DR   PANTHER; PTHR42770; AMINO ACID TRANSPORTER-RELATED; 1.
DR   PANTHER; PTHR42770:SF11; INNER MEMBRANE TRANSPORT PROTEIN YBAT; 1.
DR   Pfam; PF13520; AA_permease_2; 1.
DR   Pfam; PF00582; Usp; 2.
DR   SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 2.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        35..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        73..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        103..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        140..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        177..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        209..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        252..276
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        307..326
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        332..351
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        367..386
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        392..409
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          446..580
FT                   /note="UspA"
FT                   /evidence="ECO:0000259|Pfam:PF00582"
FT   DOMAIN          640..710
FT                   /note="UspA"
FT                   /evidence="ECO:0000259|Pfam:PF00582"
SQ   SEQUENCE   741 AA;  81554 MW;  8E000C3C04FBC48A CRC64;
     MGFLSVFSIS VGTMVGAGIF VLPGMAAAMA GPGSIISFIL SGVLALITAF CISEMATAIP
     KAGGTYVFMK RSLGSAVGSS VGIATWLGLL IKGSFAFVGF GGYLAALIAV NEIFLAVIAS
     VLFILINIVG VKSSGGIQNL MLFFLTILLF LFIFLGMGHV ELSQFVWVDT GVSETLATAG
     FVFVSYVGIA EASAIAEEVK DPGKNLPRAI IGSILFVILL YSLIMVVVVG AYPYEQLADS
     TTPILDVAED FLGSLGVTVM VLAGVFATLS TGNASLMSSA RYPFAMAKDG LMPDWLTKIN
     KKFKTPVKAI VLSGFVLTVM LLIFPVQRLA EMTSALNILV FAFVNLSLIV LREAETDWYR
     PEFKAPLYPY LPAIGFFGSL GMLFSMGELM PIVFAFSVII LGLVWYYLVK DNVKDESEVR
     GAITQRKASK ALDNFDEKTK DFEDYRVLVP ITDIKHVENL IKIAMEIAED KKGRIIPAII
     LEIPDQTPLY AYKNKYAKKR EMLEEAVLNI IEENAEYDIM EEEVIVYTHS FKKTTVDLAE
     KEDADLILLE WLDEFSHSEL LGSSVDYILH NAESDVAVFK DRGFNPTKHN KILLPTRLSS
     KIGLTLDLSS AIARKGNGFI ELLRIINPRA SSNEIEKIKE FQKRSEKRIK EESSSRIIKS
     KDVTKALINE SRKFDLVVMS ASQESALKGF LFGTIPNEVA DKTDTSVLIV QEKKSRRPKT
     TTKIKIKISG ILRWITRKIE Y
//