ID A0A1Y3GDD4_9EURY Unreviewed; 1005 AA.
AC A0A1Y3GDD4;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Signal transduction histidine kinase containing REC and PAS domain {ECO:0000313|EMBL:OUJ18323.1};
GN ORFNames=AMET1_1234 {ECO:0000313|EMBL:OUJ18323.1};
OS Methanonatronarchaeum thermophilum.
OC Archaea; Euryarchaeota; Methanonatronarchaeia; Methanonatronarchaeales;
OC Methanonatronarchaeaceae; Methanonatronarchaeum.
OX NCBI_TaxID=1927129 {ECO:0000313|EMBL:OUJ18323.1, ECO:0000313|Proteomes:UP000195137};
RN [1] {ECO:0000313|EMBL:OUJ18323.1, ECO:0000313|Proteomes:UP000195137}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AMET1 {ECO:0000313|EMBL:OUJ18323.1};
RA Sorokin D.Y., Makarova K.S., Abbas B., Ferrer M., Golyshin P.N.;
RT "Discovery of methanogenic haloarchaea.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUJ18323.1}.
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DR EMBL; MRZU01000004; OUJ18323.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y3GDD4; -.
DR OrthoDB; 230688at2157; -.
DR Proteomes; UP000195137; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00130; PAS; 2.
DR CDD; cd00156; REC; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 4.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR016120; Sig_transdc_His_kin_SpoOB.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 4.
DR PANTHER; PTHR43047:SF72; OSMOSENSING HISTIDINE PROTEIN KINASE SLN1; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF08448; PAS_4; 2.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00086; PAC; 3.
DR SMART; SM00091; PAS; 4.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 4.
DR SUPFAM; SSF55890; Sporulation response regulatory protein Spo0B; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 3.
DR PROSITE; PS50112; PAS; 2.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:OUJ18323.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 2..119
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 307..377
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 376..431
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 504..559
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 681..745
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 749..800
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 804..1005
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT MOD_RES 53
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1005 AA; 116631 MW; F45A777E7309300F CRC64;
MDVLLVDDEP SLLELAEIFL EKEYKEFNVE TVLSCEEALE LLKEDGFDCV VSDYQMPGMD
GLEFLRIVRE ERDSDIPFIV FTGRGREEVA MKALNLGADR YLQKRGDPKS QYSLLSQAIE
QEVENWRIKH RAKELKGLRS TIKEVNQVLT KYRDIKKASE NICRVLLETK GYLDISLILE
KDNVIKPVVS YGEHQRKNWE GHLKSEVDLD DQEIPDCYKQ VLKTKDKLII NSKYNSDYCL
DCTFCLYKGD HSTVKLPINL EDRRVILSVC LEVGRLDDME LELLKELRKD IQTGFKRMQT
EKKLKKSEKR YRSLIESQND LIVRVDTDNR LTFVNDAYCE LFGKTKEELK GEKFTPLIHE
DDVEHTLKQM KKLKKPPYRA TMEQRAKTKY GWRWIHWEDS AILNKDGEIK EIQGVGRDIT
ELKEKEKKLR KSEKEKSIIL ENTDEIIAYH DKNHNIQWAN KAYQKATEHT LKELKNSKCY
QAWGHNQTCK GCPVTKAIET GEPAEAELNP ENQEHWPKDQ GNWLIKASPV KDDNGDLLGA
VEVSMDITER KQAEEELRLL LENMESQAWY LKTPEKYGKV NKAHAKFLGA KKTEIENKNL
YEITKTKEEA ETCIEGNKKV FNKKQTIKTT EKVTNGQGEK RTLSITKTPK IVDGEVQYVV
CSAHDITDRI EREEELVRKN KILTNSPDIS VLLNEDGVVK YQSPVDENKL GYKIPDLVGE
NPLDYIHTED RDNIQKFFQN ILENPDEIEQ TEYRHKIPNG EYRWYENTAY NYLEDPDIEG
ILIQARDITK RKKAEEREKF LHSLLRHDLQ NKCQIVQGYL QLSKNHTLPE ELKEYLSKAE
KAVRDSLDLI EKVRTLRQIS EQEEEKQIDL DKVIKNIVTE LKDQARGKNI KIQHEKIECR
VMGGPLLQEL FRNLVENSII HSQGNKIKIS GKQTESKCII TIEDDGKGIP DKNKVFKRGY
QKGETGGTGL GLYLAKKITE NYNGTIEIKD SELGGAKFQI KLKKP
//
