ID   A0A1Y3N1H8_PIRSE        Unreviewed;       515 AA.
AC   A0A1Y3N1H8;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   RecName: Full=DNA polymerase delta catalytic subunit {ECO:0000256|ARBA:ARBA00024411};
GN   ORFNames=PIROE2DRAFT_14682 {ECO:0000313|EMBL:OUM59711.1};
OS   Piromyces sp. (strain E2).
OC   Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC   Chytridiomycota incertae sedis; Neocallimastigomycetes; Neocallimastigales;
OC   Neocallimastigaceae; Piromyces.
OX   NCBI_TaxID=73868 {ECO:0000313|EMBL:OUM59711.1, ECO:0000313|Proteomes:UP000195826};
RN   [1] {ECO:0000313|EMBL:OUM59711.1, ECO:0000313|Proteomes:UP000195826}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=E2 {ECO:0000313|EMBL:OUM59711.1,
RC   ECO:0000313|Proteomes:UP000195826};
RG   DOE Joint Genome Institute;
RA   Haitjema C.H., Gilmore S.P., Henske J.K., Solomon K.V., De Groot R.,
RA   Kuo A., Mondo S.J., Salamov A.A., Labutti K., Zhao Z., Chiniquy J.,
RA   Barry K., Brewer H.M., Purvine S.O., Wright A.T., Boxma B., Van Alen T.,
RA   Hackstein J.H., Baker S.E., Grigoriev I.V., O'Malley M.A.;
RT   "A Parts List for Fungal Cellulosomes Revealed by Comparative Genomics.";
RL   Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KZ151082; OUM59711.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y3N1H8; -.
DR   STRING; 73868.A0A1Y3N1H8; -.
DR   Proteomes; UP000195826; Unassembled WGS sequence.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR006133; DNA-dir_DNA_pol_B_exonuc.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   PANTHER; PTHR10322; DNA POLYMERASE CATALYTIC SUBUNIT; 1.
DR   PANTHER; PTHR10322:SF23; DNA POLYMERASE DELTA CATALYTIC SUBUNIT; 1.
DR   Pfam; PF03104; DNA_pol_B_exo1; 1.
DR   SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000195826}.
FT   DOMAIN          320..476
FT                   /note="DNA-directed DNA polymerase family B exonuclease"
FT                   /evidence="ECO:0000259|Pfam:PF03104"
FT   REGION          209..278
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        220..238
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        239..275
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   515 AA;  60357 MW;  7BF7F36978358E2F CRC64;
     MFSLNENFNV EFINEIEGDF HMVLDCEYIN NVYIPFDIIY NNVDLRNASY SERINILNSL
     DYNKFKNIIN KKNIKSGNNY QNIQDFITSE GDSIPNDGII ITDGQSTYFE NSKVFKIKTK
     NMDYHVVYQY KNIKKNLAIC VKYKNGSNII NHCEANEIDS TFIPFIDINE FNKACQNNNI
     FMKNNMVKEK ENKEVRNILT KGIDNNQNKS ITSTVDHCNS NKEEYSDGKD RMNDNHSTKE
     LSIIDIPKNQ KINNDSNSNT NKTNNTNNTI HHNDNPSIHN EIKNRYHRLK KLLNNSYGYN
     TTTKDRFNRL KQMLNNNINN DKLIENSIKN KNNEKRKEEF FESIEEFIKK HEKSKKDKQI
     KSNTLDEKYD IIYVETEYDL ICEFFQQIRK LDPDLIIGYN TFAFDYKYLA QRAGMYLIID
     QNNSPFTASR ILGRPTKFSN NNVSNETELK IPGRIALDMF KYAKSINLSS ASLNYVSEQL
     LNKHKIDLPY KDMFYLIYEN SEASLTKVAI GRQNL
//