ID A0A1Y3N879_PIRSE Unreviewed; 728 AA.
AC A0A1Y3N879;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Glycogen [starch] synthase {ECO:0000256|RuleBase:RU363104};
DE EC=2.4.1.11 {ECO:0000256|RuleBase:RU363104};
DE Flags: Fragment;
GN ORFNames=PIROE2DRAFT_61152 {ECO:0000313|EMBL:OUM63685.1};
OS Piromyces sp. (strain E2).
OC Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC Chytridiomycota incertae sedis; Neocallimastigomycetes; Neocallimastigales;
OC Neocallimastigaceae; Piromyces.
OX NCBI_TaxID=73868 {ECO:0000313|EMBL:OUM63685.1, ECO:0000313|Proteomes:UP000195826};
RN [1] {ECO:0000313|EMBL:OUM63685.1, ECO:0000313|Proteomes:UP000195826}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E2 {ECO:0000313|EMBL:OUM63685.1,
RC ECO:0000313|Proteomes:UP000195826};
RG DOE Joint Genome Institute;
RA Haitjema C.H., Gilmore S.P., Henske J.K., Solomon K.V., De Groot R.,
RA Kuo A., Mondo S.J., Salamov A.A., Labutti K., Zhao Z., Chiniquy J.,
RA Barry K., Brewer H.M., Purvine S.O., Wright A.T., Boxma B., Van Alen T.,
RA Hackstein J.H., Baker S.E., Grigoriev I.V., O'Malley M.A.;
RT "A Parts List for Fungal Cellulosomes Revealed by Comparative Genomics.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transfers the glycosyl residue from UDP-Glc to the non-
CC reducing end of alpha-1,4-glucan. {ECO:0000256|RuleBase:RU363104}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + H(+) + UDP; Xref=Rhea:RHEA:18549, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:58223, ChEBI:CHEBI:58885; EC=2.4.1.11;
CC Evidence={ECO:0000256|ARBA:ARBA00043769};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:18550;
CC Evidence={ECO:0000256|ARBA:ARBA00043769};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004964, ECO:0000256|RuleBase:RU363104}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 3 family.
CC {ECO:0000256|ARBA:ARBA00010686, ECO:0000256|RuleBase:RU363104}.
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DR EMBL; KZ150886; OUM63685.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y3N879; -.
DR STRING; 73868.A0A1Y3N879; -.
DR OMA; RMHKSNV; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000195826; Unassembled WGS sequence.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 6.10.260.10; -; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR008631; Glycogen_synth.
DR PANTHER; PTHR10176:SF3; GLYCOGEN [STARCH] SYNTHASE; 1.
DR PANTHER; PTHR10176; GLYCOGEN SYNTHASE; 1.
DR Pfam; PF05693; Glycogen_syn; 2.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 2.
PE 3: Inferred from homology;
KW Glycogen biosynthesis {ECO:0000256|ARBA:ARBA00023056,
KW ECO:0000256|RuleBase:RU363104};
KW Glycosyltransferase {ECO:0000256|RuleBase:RU363104};
KW Reference proteome {ECO:0000313|Proteomes:UP000195826};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363104}.
FT REGION 626..647
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:OUM63685.1"
SQ SEQUENCE 728 AA; 83603 MW; 396420F07AB167E7 CRC64;
GGIYTVIKSK TPVTATEYGE RYCLIGPLSW KTAPMEVEEI TEIPSEPLKG TLDAMRENGV
RFLYGRWLIE GAPAVLLFDI SSCRNRMDEW KGDLYKISGI PSPSDDFETN DAIVFGYIVA
WFLGEFSYRL YSKKNRVPTD MQLSNPHQLS NHHQLIHPVN IKPSVYSSYH VSNRPLIIAH
FHEWLAGVAL VLIRKRNLDI ATIFTTHATL LGRYLCAGDV DFYNNLKYFD VDSESGKRQI
YHRYCIERGA AHCADVFTTV SHITAYESEW LLKRKPDGVL PNGLNVVKFS AIHEFQNLHA
KAKEKINEFI RGHFYGHFDF DLDNTLYFFT AGRYEYRNKG VDMYIESLAR LNYKLKKSNS
NMTVVAFIIM PAATHSFTVD ALKGQAVMKQ LRQTVADMQE SIGKRILASA ARGSLPDPAN
LLSDEEMIVL KRRIYALKRD SLPPIVTHNM ADDAHDPILN HIRRVRLFNA PSDRVKIIFH
PEFLNSNNPI LPLDYEEFVR GCHLGVFASY YEPWGYTPAE CTVMGVPSIT TNLSGFGCFM
EEMITHPADY GIYIVNRRTC SVEESVEQLA NCMFDFTKKT RRQRINQRNR TERLSDLLDW
KRMGIEYQKA RWVAVLRKWP EISSLENEEE DDQNLNLDEQ SLPDEQTMSE GEETILGRKM
RKVPRPPSAP GSPRILESFS EQEFDTWKDM NKTEGVQDTV IDDLKKLNVS GHQNFIDNYD
DADDDDEE
//
