ID A0A1Y3SF75_9FIRM Unreviewed; 977 AA.
AC A0A1Y3SF75;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=2-hydroxyglutaryl-CoA dehydratase {ECO:0000313|EMBL:OUN20669.1};
GN ORFNames=B5G34_14190 {ECO:0000313|EMBL:OUN20669.1};
OS Flavonifractor sp. An82.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Flavonifractor.
OX NCBI_TaxID=1965660 {ECO:0000313|EMBL:OUN20669.1, ECO:0000313|Proteomes:UP000196422};
RN [1] {ECO:0000313|Proteomes:UP000196422}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An82 {ECO:0000313|Proteomes:UP000196422};
RA Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA Rychlik I.;
RT "Function of individual gut microbiota members based on whole genome
RT sequencing of pure cultures obtained from chicken caecum.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUN20669.1}.
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DR EMBL; NFHG01000016; OUN20669.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y3SF75; -.
DR OrthoDB; 9802715at2; -.
DR Proteomes; UP000196422; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.420.40; -; 4.
DR InterPro; IPR002731; ATPase_BadF.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR018709; CoA_activase_DUF2229.
DR InterPro; IPR008275; CoA_E_activase_dom.
DR NCBIfam; TIGR00241; CoA_E_activ; 2.
DR PANTHER; PTHR32329:SF4; ACTIVATOR OF 2-HYDROXYACYL-COA DEHYDRATASE-RELATED; 1.
DR PANTHER; PTHR32329; BIFUNCTIONAL PROTEIN [INCLUDES 2-HYDROXYACYL-COA DEHYDRATASE (N-TER) AND ITS ACTIVATOR DOMAIN (C_TERM)-RELATED; 1.
DR Pfam; PF01869; BcrAD_BadFG; 2.
DR Pfam; PF09989; DUF2229; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023014};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00023014}.
FT DOMAIN 5..255
FT /note="ATPase BadF/BadG/BcrA/BcrD type"
FT /evidence="ECO:0000259|Pfam:PF01869"
FT DOMAIN 319..573
FT /note="ATPase BadF/BadG/BcrA/BcrD type"
FT /evidence="ECO:0000259|Pfam:PF01869"
FT DOMAIN 664..880
FT /note="DUF2229"
FT /evidence="ECO:0000259|Pfam:PF09989"
SQ SEQUENCE 977 AA; 107204 MW; 630EFAB79EC68EDD CRC64;
MSLRIGIDIG STTVKVVVLD EANQLLFRSY ERHYSKARER AAETLRSIEE KLRGQQVRIA
ITGSAGLGVA KAAEIDFVQE VYATAAAVNT YIPATDAVIE LGGEDAKIIF FGGALEERMN
GSCAGGTGAF IDQMATLMNV SVNELDELSL KHEKIYPIAS RCGVFAKSDI QPILNQGGRK
EDVAASIFQA VVDQTVAGLT QGRELKGKIV FLGGPLHFLK GLRQRFVETL KLDEEHAIFP
EDGDCFAGIG AALCATELAE RSFDEILERL EKSVDNVGLV DTMPPLFNDQ GEYDAFLARH
NAMHPPEVDV NTYSGDAWLG IDAGSTTTKM VLITADGGLL YTYYHSNLGN PVAIVLEQLK
EIYALCGDRI TIKGAAVTGY GEELIKNAFS CDAGLVETVA HYNAARHFNP DVDFIIDIGG
QDMKCFKIRN GAVDSIMLNE ACSSGCGSFI ETFAKALGYN IADFSKLGLL AKHPVNLGSR
CTVFMNSSVK QAQKDGASVE DISAGLSISI VKNAVYKVIR AANADDLGKH IVVQGGTFHN
DAVLRAFELE LGRNVTRPTI AGIMGAFGAA LAARDLHLDK SSILTAEDLK SFSHTARPVT
CNLCTNHCSL TVNTFDGGRR FISGNRCSRP LGKAKVENPD LMNYKYKKLR ALHGKGSGNG
VRGKMGIPFG LNMYENLPFW FEFFTRLNFE VVLSPESSRK LYLKGQHTIP SDTVCYPAKL
LHGHVEALVE EGVDAIWYPC MSYNNDEGIG DNHYNCPVVA YYPELLAANV PLLKQTRFLN
PYVGLWRHKD FTKRIAKIMD EEFSIPKRET EAAAKAAYAA YDAYVHDVRE TGKRYIEYAR
AHDMPIIVAC GRPYHIDPEI NHGINDLITS FGFVLVTEDA LSYLEGYAPR KVLNQWTFQS
RMYNAARYVC TQPDMQVVQL VSFGCGTDAI TTDELRDILE SGGKLYTQLK IDDISNLGAV
TIRVRSLMAA MDARKHQ
//
