ID   A0A1Y3SFK2_9FIRM        Unreviewed;       479 AA.
AC   A0A1Y3SFK2;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Amino acid carrier protein {ECO:0000313|EMBL:OUN22095.1};
GN   ORFNames=B5G34_08655 {ECO:0000313|EMBL:OUN22095.1};
OS   Flavonifractor sp. An82.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Flavonifractor.
OX   NCBI_TaxID=1965660 {ECO:0000313|EMBL:OUN22095.1, ECO:0000313|Proteomes:UP000196422};
RN   [1] {ECO:0000313|Proteomes:UP000196422}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=An82 {ECO:0000313|Proteomes:UP000196422};
RA   Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA   Rychlik I.;
RT   "Function of individual gut microbiota members based on whole genome
RT   sequencing of pure cultures obtained from chicken caecum.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC       (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC       ECO:0000256|RuleBase:RU363064}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUN22095.1}.
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DR   EMBL; NFHG01000006; OUN22095.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y3SFK2; -.
DR   OrthoDB; 9804874at2; -.
DR   Proteomes; UP000196422; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   NCBIfam; TIGR00835; agcS; 1.
DR   PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR   PANTHER; PTHR30330:SF1; AMINO-ACID CARRIER PROTEIN ALST; 1.
DR   Pfam; PF01235; Na_Ala_symp; 1.
DR   PRINTS; PR00175; NAALASMPORT.
DR   PROSITE; PS00873; NA_ALANINE_SYMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU363064};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW   Symport {ECO:0000256|RuleBase:RU363064};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT   TRANSMEM        15..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        74..93
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        99..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        146..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        186..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        212..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        244..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        307..329
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        349..374
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        386..407
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        413..433
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
SQ   SEQUENCE   479 AA;  51672 MW;  2EBC68FA61BC2B69 CRC64;
     MAFFGSFLSN TSNFLYTYIL IALLIFAGLY FTIRTKGVQF RLFPEAIRVL GERKKDGKDI
     SSFQALMIST ASRVGTGNIA GVANAIIAAT VIGGYGAVFW MWLLALIGAA SAFIESTLAQ
     CYKEKHGENW VGGPAYYIQK ALGSRFFGVV FAVLLIACFA YGFNALQAYN AGSALQYYLP
     NYATSIWPAV VGAVLAILTG VCIFGGVRRI SAITSGIVPV MAAIYIALGL FITVKNIGQV
     PHMISLIFSQ AFDPKAMFAG IGASCIMQGI KRGLYSNEAG MGSAPNAAAA ADVSHPVKQG
     LVQMLSVFID TILICSTTAF MLLLSGVPID AYSEGMNFVQ AAVHAQVGPF GPIFITVSIF
     LFAFSSLVGN YYYTESNFRF IRDSKVGLLI FRLTCVAAIF IGAQMSFSMV WDLADVLMGL
     MALVNLVAIL LLGGKALKVL KDYVDQKKAG KNPVYRYEEV GIGDPEIWDE AHARKWEGR
//