ID A0A1Y3SH16_9FIRM Unreviewed; 1136 AA.
AC A0A1Y3SH16;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OUN23551.1};
GN ORFNames=B5G34_00095 {ECO:0000313|EMBL:OUN23551.1};
OS Flavonifractor sp. An82.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Flavonifractor.
OX NCBI_TaxID=1965660 {ECO:0000313|EMBL:OUN23551.1, ECO:0000313|Proteomes:UP000196422};
RN [1] {ECO:0000313|Proteomes:UP000196422}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An82 {ECO:0000313|Proteomes:UP000196422};
RA Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA Rychlik I.;
RT "Function of individual gut microbiota members based on whole genome
RT sequencing of pure cultures obtained from chicken caecum.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=adenosylcob(III)alamin; Xref=ChEBI:CHEBI:18408;
CC Evidence={ECO:0000256|ARBA:ARBA00001922};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUN23551.1}.
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DR EMBL; NFHG01000001; OUN23551.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y3SH16; -.
DR OrthoDB; 9762933at2; -.
DR Proteomes; UP000196422; Unassembled WGS sequence.
DR GO; GO:0031419; F:cobalamin binding; IEA:UniProtKB-KW.
DR GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.
DR CDD; cd00081; Hint; 1.
DR Gene3D; 3.20.70.20; -; 2.
DR Gene3D; 2.170.16.10; Hedgehog/Intein (Hint) domain; 2.
DR Gene3D; 3.10.28.10; Homing endonucleases; 1.
DR InterPro; IPR003587; Hint_dom_N.
DR InterPro; IPR036844; Hint_dom_sf.
DR InterPro; IPR027434; Homing_endonucl.
DR InterPro; IPR006142; INTEIN.
DR InterPro; IPR030934; Intein_C.
DR InterPro; IPR004042; Intein_endonuc.
DR InterPro; IPR006141; Intein_N.
DR InterPro; IPR004860; LAGLIDADG_2.
DR InterPro; IPR000788; RNR_lg_C.
DR NCBIfam; TIGR01443; intein_Cterm; 1.
DR NCBIfam; TIGR01445; intein_Nterm; 1.
DR PANTHER; PTHR43371:SF1; RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE; 1.
DR PANTHER; PTHR43371; VITAMIN B12-DEPENDENT RIBONUCLEOTIDE REDUCTASE; 1.
DR Pfam; PF14890; Intein_splicing; 1.
DR Pfam; PF14528; LAGLIDADG_3; 1.
DR Pfam; PF02867; Ribonuc_red_lgC; 2.
DR PRINTS; PR00379; INTEIN.
DR PRINTS; PR01183; RIBORDTASEM1.
DR SMART; SM00306; HintN; 1.
DR SUPFAM; SSF51294; Hedgehog/intein (Hint) domain; 1.
DR SUPFAM; SSF55608; Homing endonucleases; 1.
DR SUPFAM; SSF51998; PFL-like glycyl radical enzymes; 2.
DR PROSITE; PS50818; INTEIN_C_TER; 1.
DR PROSITE; PS50819; INTEIN_ENDONUCLEASE; 1.
DR PROSITE; PS50817; INTEIN_N_TER; 1.
PE 4: Predicted;
KW Autocatalytic cleavage {ECO:0000256|ARBA:ARBA00022813};
KW Cobalamin {ECO:0000256|ARBA:ARBA00022628};
KW Cobalt {ECO:0000256|ARBA:ARBA00023285};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Protein splicing {ECO:0000256|ARBA:ARBA00023000}.
FT DOMAIN 284..385
FT /note="DOD-type homing endonuclease"
FT /evidence="ECO:0000259|PROSITE:PS50819"
FT DOMAIN 494..516
FT /note="Intein C-terminal splicing"
FT /evidence="ECO:0000259|PROSITE:PS50818"
SQ SEQUENCE 1136 AA; 127353 MW; 9FF0375DD5FAA963 CRC64;
MNDIHTVEEW LGKDNKLGQD IWHKKYQKNE ETFDAWLDRV SLGNPAYRRL IELKMLIPGG
RILSNVGIDD DSCGMSNCYS RGFIEDDYND IMQAAVDIGK TFKSQGGQGL SLSKLRPKGT
PIGDNYESDG IVPFMKIYNE VTQGTSQGGC IEENELVLTS EGYKPIKDIE VGDNVYTKAG
YKPVLTVWDK GEQETYKVTT KKGYTISTTI DHKYCVDGFN VSPLSSLNIG DKICLITSQP
NNIKKELNEK AYFFAHFLAN GYIRKDNTGN ITMHKKYKEV GDKLISYLSS LGFNAYYNNR
EDEDAIRIVL TVPVCKWIKK QVKKDTCSYI RVPDWVLNGD DDCVLSFVGG AIDSDGSVRR
NSICCDTICE AYAEQISLLM KRVGLFPTIS VNYRENENNK RPIYRVSDSI RDDILTYYSY
KVAKTHVPYA KNSKYVTPYT MKNTGLSKND AKHLAKISKN TNIGLYTYLQ VKDKPYAPMI
LDEISNIEYI GIRHVYDIEV ADEHKFFCNG IYVSNSRKGA LLMSLDAWHK EVMNFITIKS
EEGLIEKANL SLEIDNEFME CVQAYYERGE TKTITRKESY SGHEIEWEVT PIEVFKAFIH
NNYEWGDPGC LFVDKFRNYN LMEFCDNYQI ESCNPCGEQP LPKHGACNLA AINLSEFVVN
PYTNDAGFDF DAFEAAVMLG IQYLDKIVDF NANRHALPQQ KKMALEFRNC GLGVMGYATM
LMKLGLQYGS DDAIRFSDDL FSYMFVTAVR SSSQEAKKLG TFPGYRDQIF NSNIILNHFG
NGAISDLRSI GLRNCSLLSI APTGSIATML GESGGIEPEF AISYTRRTVG LTDNEDHYYT
VYCKAAREYL SSHPECDGVL PEWFVSSADI DPIRRVKTQA VIQKHIDTAI SSTVNLPEAA
SEDDMARIYI EAWKQGTKGL TIFRSGCKRE AILTTGDTAP KKNEQKNDTC TDCLNRGMII
GVDDDLMSIK KTIINGCGKF YLHVDFDETS LEFLETYIDI GSGGGCERNL QFISRLMSLA
LRAGVPLEAI IDQAYSIRPC NAYLARTKSK GDTSPGTSCP SAIGKALEEM KKKAVYLYGD
DTEEAPEVVS DPAAKKANNT KTNHNDSPSK CPECGAQLRF EGGCDVCPEC GYSHCG
//
