ID A0A1Y3TAU3_9FIRM Unreviewed; 333 AA.
AC A0A1Y3TAU3;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:OUN33681.1};
GN ORFNames=B5G27_11785 {ECO:0000313|EMBL:OUN33681.1};
OS Lachnoclostridium sp. An76.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1965654 {ECO:0000313|EMBL:OUN33681.1, ECO:0000313|Proteomes:UP000199802};
RN [1] {ECO:0000313|Proteomes:UP000199802}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An76 {ECO:0000313|Proteomes:UP000199802};
RA Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA Rychlik I.;
RT "Function of individual gut microbiota members based on whole genome
RT sequencing of pure cultures obtained from chicken caecum.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUN33681.1}.
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DR EMBL; NFHL01000006; OUN33681.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y3TAU3; -.
DR OrthoDB; 9789891at2; -.
DR Proteomes; UP000199802; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR PANTHER; PTHR30146:SF109; TRANSCRIPTIONAL REGULATOR LACI_GALR-LIKE SENSOR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000199802};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 2..50
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 333 AA; 37051 MW; D201D37D8DE99A42 CRC64;
MTTIQDIADK LGISKGTVSK ALNDAPDISE TLQKQILETA VELGYTKLRR YKKTAKRLCV
IAQKDNIEYL EPHHFAYDIV MGFRQMSEPA GFEVDVVPVD VELQRETSFD VFMLQNDYAG
AFVLGFSLGE PWMKDFQATR TPTVLYDNHI IGNPATAYVG IDNDEGMYLA VGYLKKQGHQ
KIGYLSSALG SHIMQVRHRA FFQAMHRHGL KADSSYSGCS YYLSECMEKH LPRFLDMGMT
AVICCQDTFA SAAITQCQQL GYQVPRDISI IGFDDIPICP YTSPPLTTVR QDRTELGKSG
YYALSSLMNG VSIGTVLLHA DLIVRGSTAA PRQ
//
