ID A0A1Y3VNW1_9BACT Unreviewed; 462 AA.
AC A0A1Y3VNW1;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Pseudouridine synthase {ECO:0000256|RuleBase:RU003887};
DE EC=5.4.99.- {ECO:0000256|RuleBase:RU003887};
GN ORFNames=B5G13_18925 {ECO:0000313|EMBL:OUN62742.1};
OS Butyricimonas sp. An62.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Odoribacteraceae;
OC Butyricimonas.
OX NCBI_TaxID=1965649 {ECO:0000313|EMBL:OUN62742.1, ECO:0000313|Proteomes:UP000196559};
RN [1] {ECO:0000313|Proteomes:UP000196559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An62 {ECO:0000313|Proteomes:UP000196559};
RA Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA Rychlik I.;
RT "Function of individual gut microbiota members based on whole genome
RT sequencing of pure cultures obtained from chicken caecum.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the pseudouridine synthase RsuA family.
CC {ECO:0000256|ARBA:ARBA00008348, ECO:0000256|RuleBase:RU003887}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUN62742.1}.
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DR EMBL; NFHW01000006; OUN62742.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y3VNW1; -.
DR OrthoDB; 9807213at2; -.
DR Proteomes; UP000196559; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0120159; F:rRNA pseudouridine synthase activity; IEA:UniProt.
DR GO; GO:0000455; P:enzyme-directed rRNA pseudouridine synthesis; IEA:UniProt.
DR CDD; cd02870; PseudoU_synth_RsuA_like; 1.
DR CDD; cd00165; S4; 1.
DR Gene3D; 3.30.70.1560; Alpha-L RNA-binding motif; 1.
DR Gene3D; 3.30.70.580; Pseudouridine synthase I, catalytic domain, N-terminal subdomain; 1.
DR Gene3D; 3.10.290.10; RNA-binding S4 domain; 1.
DR InterPro; IPR042092; PsdUridine_s_RsuA/RluB/E/F_cat.
DR InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR InterPro; IPR006145; PsdUridine_synth_RsuA/RluA.
DR InterPro; IPR000748; PsdUridine_synth_RsuA/RluB/E/F.
DR InterPro; IPR018496; PsdUridine_synth_RsuA/RluB_CS.
DR InterPro; IPR002942; S4_RNA-bd.
DR InterPro; IPR036986; S4_RNA-bd_sf.
DR InterPro; IPR020094; TruA/RsuA/RluB/E/F_N.
DR NCBIfam; TIGR00093; pseudouridine synthase; 1.
DR PANTHER; PTHR47683; PSEUDOURIDINE SYNTHASE FAMILY PROTEIN-RELATED; 1.
DR PANTHER; PTHR47683:SF2; S4 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00849; PseudoU_synth_2; 1.
DR Pfam; PF01479; S4; 1.
DR SMART; SM00363; S4; 1.
DR SUPFAM; SSF55174; Alpha-L RNA-binding motif; 1.
DR SUPFAM; SSF55120; Pseudouridine synthase; 1.
DR PROSITE; PS01149; PSI_RSU; 1.
DR PROSITE; PS50889; S4; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU003887};
KW Reference proteome {ECO:0000313|Proteomes:UP000196559};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00182}.
FT DOMAIN 231..298
FT /note="RNA-binding S4"
FT /evidence="ECO:0000259|SMART:SM00363"
FT REGION 1..216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 462 AA; 55121 MW; 87F2016804CB176E CRC64;
MNRETKRPRI TRPIENRDEN RRSRTPRFEN REGGESETRR PNRFNTDRPR REQGHGYIRD
LNKERERERN EGTGDRDNGN RYYRDSDRNR ERGDRENNRY ENRDNRRSYE RGNRDNNRFS
DRGERRERRP QDRDENAERR DNRYQNRDRN DRREEGRRER GSREEGGRGE GYRGDRRDRR
EGDDRRDRYS DRPARKVFTR RADGDGAPKS VYSKKKQIEY RKKNEGQETE LRLNRYIAKG
GVCSRRDADV LIAAGRVKVN GEVVQQVGVK VKRTDRVEVD DQVITPERKV YLVLNKPKDY
VTTVEDPLER RTVMTLIEGA CKERVYPIGR LDRQTTGVLL FTNDGDLAKK LTHPKYNQKK
IYHVFLDKVV QTGDLEAIRK GIDLEDGFIQ ADDVRVAEDD RTQVGIEIHS GRNRIVRRIF
EHLGYQILRL DRVFFAGITK KNLPRGHWRF LTEDEVNILK AY
//
