ID A0A1Y3WIP9_9BACT Unreviewed; 846 AA.
AC A0A1Y3WIP9;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Zinc-dependent metalloprotease {ECO:0008006|Google:ProtNLM};
GN ORFNames=B5G10_09925 {ECO:0000313|EMBL:OUN70839.1};
OS Barnesiella sp. An55.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Barnesiellaceae;
OC Barnesiella.
OX NCBI_TaxID=1965646 {ECO:0000313|EMBL:OUN70839.1, ECO:0000313|Proteomes:UP000196624};
RN [1] {ECO:0000313|Proteomes:UP000196624}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An55 {ECO:0000313|Proteomes:UP000196624};
RA Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA Rychlik I.;
RT "Function of individual gut microbiota members based on whole genome
RT sequencing of pure cultures obtained from chicken caecum.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUN70839.1}.
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DR EMBL; NFHZ01000015; OUN70839.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y3WIP9; -.
DR OrthoDB; 9776599at2; -.
DR Proteomes; UP000196624; Unassembled WGS sequence.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR CDD; cd04276; ZnMc_MMP_like_2; 1.
DR Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR InterPro; IPR033413; DUF5117.
DR InterPro; IPR033428; DUF5118.
DR InterPro; IPR032534; EcxA_zinc-bd.
DR InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR InterPro; IPR034032; Zn_MMP-like_bac.
DR PANTHER; PTHR38478; PEPTIDASE M1A AND M12B; 1.
DR PANTHER; PTHR38478:SF1; ZINC DEPENDENT METALLOPROTEASE DOMAIN LIPOPROTEIN; 1.
DR Pfam; PF16313; DUF4953; 1.
DR Pfam; PF17148; DUF5117; 1.
DR Pfam; PF17162; DUF5118; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000196624};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..846
FT /note="Zinc-dependent metalloprotease"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013164383"
FT DOMAIN 45..93
FT /note="DUF5118"
FT /evidence="ECO:0000259|Pfam:PF17162"
FT DOMAIN 102..281
FT /note="DUF5117"
FT /evidence="ECO:0000259|Pfam:PF17148"
FT DOMAIN 414..723
FT /note="EcxA zinc-binding"
FT /evidence="ECO:0000259|Pfam:PF16313"
SQ SEQUENCE 846 AA; 96447 MW; 4DE15254F8DD64F3 CRC64;
MKKLVWAILA TLLIAGASPA NCYAKRKSKK EDKKEQVKDT TAKESKYEKL VKGAKTQKGM
FTLHITTDNK LLVEIPDSLM SRIFLLSSRV AATTNPKLFV AGEMTTDPFM IRFSKNGQSV
FMHLVQHSNI IDQNDPIAAS FDKNFGDPIV KAFKIEVQNG NSVVVDMSDF FKTNEKIISP
MPSNPSSKIK TGTYTAANSY ILGAKSFPKN CEIRSVLSFT GDNNCTVTMH RSLVLLPEQP
MRPRIYDRRV GFFSSTKNIY TSDKDRIDRT QYIHRWRLEP KDEDREAYFR GELVEPKKPI
VFYVDSAFPE KWRDIVKQGV EDWNTAFEAA GFKNAVIARD YPQNDPDFDP DDMRYSCVKY
AVTDIANAMG PSYVDPRSGE ILTADVIWYH NVISLVHDWR FAQTGAVDPR VRKETFDNDV
MRESLRYVAS HEIGHTLGLM HNMGASYAFT IDSLRSPSFT QKYGTTPSIM DYARNNFVAQ
PGDYERGVRL TPPILGVYDI YAINWGYRLI ADAPTPQDEV ATLDRWIAEK KADPMYTFGA
QQYPDTYDPT DQTEDLSNDH FKAGEMAISN LKIIVKNFEK WLFDEGKDYR TIRDEYTALV
QQYNRHLRHV VPYIGGVLYT EVRQGDDTLP YTYLDKATQR KALKWILNQA RTYRDWLTPA
DLLQRIGANV NYASSIHRTL PASLIKPATL FRIREGGAID PVKNYTVDSY LNDVIAEVFK
ATYQGRKLNE VERDLQSETI NLLARYSNLE NTPVKSASTS RLTDDVDLEG APFPCSHVLC
HQAWEQSFTR FTIGPSMSVA EMAPYMSGAL KKILTLYKQK RAATTDSATR DFYDYQIVTI
EKLFNN
//
