ID A0A1Y3XBT2_9FIRM Unreviewed; 468 AA.
AC A0A1Y3XBT2;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Guanine permease {ECO:0008006|Google:ProtNLM};
GN ORFNames=B5G06_08910 {ECO:0000313|EMBL:OUN83005.1};
OS Flavonifractor sp. An52.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Flavonifractor.
OX NCBI_TaxID=1965642 {ECO:0000313|EMBL:OUN83005.1, ECO:0000313|Proteomes:UP000195424};
RN [1] {ECO:0000313|Proteomes:UP000195424}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An52 {ECO:0000313|Proteomes:UP000195424};
RA Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA Rychlik I.;
RT "Function of individual gut microbiota members based on whole genome
RT sequencing of pure cultures obtained from chicken caecum.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUN83005.1}.
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DR EMBL; NFIB01000019; OUN83005.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y3XBT2; -.
DR Proteomes; UP000195424; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000195424};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 28..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 129..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 161..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 362..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 412..438
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 450..466
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 468 AA; 49124 MW; 342C5A959AFA8D37 CRC64;
MPTRIICLRW SSGDGGCQHK RRWHNRTCWV CGFLDYSITT FFAMAYIIFV NPNTLCANVG
TQAQPFFPAM PESLWGPVLV ATCVSAAIGC FLTGLLANLP FAQAPGMGLN AFFTYTVCLG
MGYTWQEGLA IVLLSGLLFL AFTLSPLRGK LIRAIPDFMK HAISAGIGLF IALIGLLNVK
VITLSGTVPA LQLSTLVDGQ RVWNVQGLLA LAGLLLTAVL MAFRVKGAVV LGIVITTLVG
LPLGVTQIPE TVTMEHITLA PVLFQMDLGG VLEKGLLPLL TAVISFAIVD CFDTLGALVG
LSANVGLKEG TEKRGERALV ADALATCCGA CVGTSTVSTF AESAAGIAEG ARTGLSSMVV
GVLFLCSVFL APVAGIIPAA ATAPALIIVG VLTMRSAASI PWDDLECAVP AFLTIAVMPF
AYSISDGIAF GLISYCLIKM LRGKGREVSA FTYGIAVIFA LKYVLANL
//
