ID A0A1Y3XL14_9FIRM Unreviewed; 629 AA.
AC A0A1Y3XL14;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Peptidase S41 {ECO:0008006|Google:ProtNLM};
GN ORFNames=B5G06_06490 {ECO:0000313|EMBL:OUN83829.1};
OS Flavonifractor sp. An52.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Flavonifractor.
OX NCBI_TaxID=1965642 {ECO:0000313|EMBL:OUN83829.1, ECO:0000313|Proteomes:UP000195424};
RN [1] {ECO:0000313|Proteomes:UP000195424}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An52 {ECO:0000313|Proteomes:UP000195424};
RA Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA Rychlik I.;
RT "Function of individual gut microbiota members based on whole genome
RT sequencing of pure cultures obtained from chicken caecum.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S41A family.
CC {ECO:0000256|ARBA:ARBA00009179}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUN83829.1}.
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DR EMBL; NFIB01000012; OUN83829.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y3XL14; -.
DR Proteomes; UP000195424; Unassembled WGS sequence.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00988; PDZ_CTP_protease; 1.
DR CDD; cd07560; Peptidase_S41_CPP; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 3.30.750.44; -; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR041489; PDZ_6.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR004447; Peptidase_S41A.
DR InterPro; IPR001119; SLH_dom.
DR InterPro; IPR005151; Tail-specific_protease.
DR PANTHER; PTHR32060:SF22; CARBOXYL-TERMINAL-PROCESSING PEPTIDASE 2, CHLOROPLASTIC-RELATED; 1.
DR PANTHER; PTHR32060; TAIL-SPECIFIC PROTEASE; 1.
DR Pfam; PF17820; PDZ_6; 1.
DR Pfam; PF03572; Peptidase_S41; 1.
DR Pfam; PF00395; SLH; 2.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00245; TSPc; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS51272; SLH; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022825};
KW Protease {ECO:0000256|ARBA:ARBA00022825};
KW Reference proteome {ECO:0000313|Proteomes:UP000195424};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..629
FT /note="Peptidase S41"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5038532218"
FT DOMAIN 76..140
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 436..494
FT /note="SLH"
FT /evidence="ECO:0000259|PROSITE:PS51272"
FT DOMAIN 496..559
FT /note="SLH"
FT /evidence="ECO:0000259|PROSITE:PS51272"
SQ SEQUENCE 629 AA; 66711 MW; FB1C2E61E9BB40ED CRC64;
MKLRFRLPAV GLAASLLLTT AAQALNPSQA LTLLNWYYLD PLPDQVFEQT DMNGIIQALG
DPYTEYFTAE EYAAFHASLS DSELVGAGVS IQLADDGLLV TRVIPGSAAE AGGLLAGDVI
TAIDGQSCMK ISLEQASALL GGEVGTSFQL TYLRDGQAHT VTLTRCAFVV PTAYTELWED
HIGYVACDAF GPETAGHVQE GLETYGSQAD HWIMDLRNNG GGEVTAALNT ISYFAGPNDQ
LVYMRASDGS INAQGSQSAQ ITDEPLIVLT NFYSASASEL FAAAIRDTGS GLLVGDRTYG
KGVAQILLDS TLFPAFFSEG DALKMTAYRF FGPAGTSNDT IGVMPHLLLN PSLADEAAVL
LSSPEPQGDT SGTARIDLNG AWYIDLEQAC STSYQAAFTA LLEALPDGVL LRTGTGDGWE
ATTAADLAAA CGLSGYHHRG FSDTDQSPYA DEIGLLATYG VVLGAGDGTY RPAEALTRGQ
LCTLLAQALN CKVPTGESAF TDVSMDDWYG PSVNALASMG LVNGVGGGRF APNDPVSHEQ
FITILSRLGR KLDLDLIQTW QNRPEAAFAE YQNYSSWSWE SVWLLAQDED GLLWAAPSEI
DPAGVTTREE AAALTCTLLC KLNLLPSLI
//
