ID A0A1Y4AEI2_9BACE Unreviewed; 393 AA.
AC A0A1Y4AEI2;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Aminopeptidase {ECO:0000256|PIRNR:PIRNR005700};
GN ORFNames=B5F91_07430 {ECO:0000313|EMBL:OUO20232.1};
OS Bacteroides sp. An322.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=1965632 {ECO:0000313|EMBL:OUO20232.1, ECO:0000313|Proteomes:UP000195527};
RN [1] {ECO:0000313|Proteomes:UP000195527}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An322 {ECO:0000313|Proteomes:UP000195527};
RA Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA Rychlik I.;
RT "Function of individual gut microbiota members based on whole genome
RT sequencing of pure cultures obtained from chicken caecum.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|PIRNR:PIRNR005700}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUO20232.1}.
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DR EMBL; NFIN01000010; OUO20232.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y4AEI2; -.
DR OrthoDB; 9814054at2; -.
DR Proteomes; UP000195527; Unassembled WGS sequence.
DR GO; GO:0070005; F:cysteine-type aminopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR000169; Pept_cys_AS.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR InterPro; IPR004134; Peptidase_C1B.
DR PANTHER; PTHR10363; BLEOMYCIN HYDROLASE; 1.
DR PANTHER; PTHR10363:SF2; BLEOMYCIN HYDROLASE; 1.
DR Pfam; PF00112; Peptidase_C1; 1.
DR Pfam; PF03051; Peptidase_C1_2; 1.
DR PIRSF; PIRSF005700; PepC; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000256|PIRNR:PIRNR005700,
KW ECO:0000313|EMBL:OUO20232.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PIRNR:PIRNR005700};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PIRNR:PIRNR005700};
KW Reference proteome {ECO:0000313|Proteomes:UP000195527};
KW Signal {ECO:0000256|SAM:SignalP};
KW Thiol protease {ECO:0000256|ARBA:ARBA00022807,
KW ECO:0000256|PIRNR:PIRNR005700}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..393
FT /note="Aminopeptidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013073748"
FT DOMAIN 34..161
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00112"
FT ACT_SITE 48
FT /evidence="ECO:0000256|PIRSR:PIRSR005700-1"
FT ACT_SITE 328
FT /evidence="ECO:0000256|PIRSR:PIRSR005700-1"
FT ACT_SITE 349
FT /evidence="ECO:0000256|PIRSR:PIRSR005700-1"
SQ SEQUENCE 393 AA; 44429 MW; F7358E4F26D6D9C8 CRC64;
MKLNYFTLAA LFFIPLSGTA QSENGYQFTT VVQQKATPVK DQAVSGTCWC FATTSFIESE
LLRQGKGEYD LSEMFIVRQK YLNQMADNLL RHGKGNVTQG SITASWITAF NQVGIVPEEA
YTGINYDSPV HNHSELAGYV EAISAEAVKQ KKNSKQYQEL ANSLFDIYMG KVPETFTYKG
KEYTPKSFAE SLGIDTDDYI PLTSFTHKPY YKPFEVEIPD NWEHSQMYNL PLDELISVMD
GALKSGYTLC WDGDVSEKGF AYLNGVAINP DVKSDDLYKD SDRAHWGQLN DTERLAEVFR
FEHPYPEVKV TPEIRQQGYE SGKTTDDHLM HITGIATDQN GTKYYITKNS WAADSNDFGG
YLNMSESYVR AKTIYILVHK DALPKTLKEK LGI
//
