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Database: UniProt
Entry: A0A1Y4AU91_9FIRM
LinkDB: A0A1Y4AU91_9FIRM
Original site: A0A1Y4AU91_9FIRM 
ID   A0A1Y4AU91_9FIRM        Unreviewed;       681 AA.
AC   A0A1Y4AU91;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   10-APR-2019, entry version 5.
DE   RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN   ORFNames=B5F86_11990 {ECO:0000313|EMBL:OUO25857.1};
OS   Lachnoclostridium sp. An298.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Lachnospiraceae.
OX   NCBI_TaxID=1965627 {ECO:0000313|EMBL:OUO25857.1, ECO:0000313|Proteomes:UP000199801};
RN   [1] {ECO:0000313|EMBL:OUO25857.1, ECO:0000313|Proteomes:UP000199801}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=An298 {ECO:0000313|EMBL:OUO25857.1,
RC   ECO:0000313|Proteomes:UP000199801};
RA   Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T.,
RA   Cizek A., Rychlik I.;
RT   "Function of individual gut microbiota members based on whole genome
RT   sequencing of pure cultures obtained from chicken caecum.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake
CC       system. {ECO:0000256|RuleBase:RU362098}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-
CC       like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:OUO25857.1}.
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DR   EMBL; NFIS01000033; OUO25857.1; -; Genomic_DNA.
DR   Proteomes; UP000199801; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   CDD; cd01879; FeoB; 1.
DR   InterPro; IPR003373; Fe2_transport_prot-B.
DR   InterPro; IPR011640; Fe2_transport_prot_B_C.
DR   InterPro; IPR041069; FeoB_Cyto.
DR   InterPro; IPR030389; G_FEOB_dom.
DR   InterPro; IPR011642; Gate_dom.
DR   InterPro; IPR006073; GTP_binding_domain.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   Pfam; PF07664; FeoB_C; 1.
DR   Pfam; PF17910; FeoB_Cyto; 1.
DR   Pfam; PF02421; FeoB_N; 1.
DR   Pfam; PF07670; Gate; 2.
DR   PRINTS; PR00326; GTP1OBG.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00437; feoB; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51711; G_FEOB; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000199801};
KW   GTP-binding {ECO:0000256|RuleBase:RU362098};
KW   Ion transport {ECO:0000256|RuleBase:RU362098};
KW   Iron {ECO:0000256|RuleBase:RU362098};
KW   Iron transport {ECO:0000256|RuleBase:RU362098};
KW   Membrane {ECO:0000256|RuleBase:RU362098};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199801};
KW   Transmembrane {ECO:0000256|RuleBase:RU362098};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU362098};
KW   Transport {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    291    311       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    346    375       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    395    419       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    431    453       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    459    481       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    519    538       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    572    599       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    611    637       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    657    680       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   DOMAIN        5    167       FeoB-type G. {ECO:0000259|PROSITE:
FT                                PS51711}.
SQ   SEQUENCE   681 AA;  75446 MW;  4CCDBA09DD9C0D8E CRC64;
     MSGKVINVGF IGNPNCGKTT LFNAYTGANL KVANWPGVTV EKKEGYTTYK EQEFKLIDLP
     GIYSLTSYTM EEKVSRECIM SDEVDVIVDV VDASCLERNL YLTLQLIELG KPVVLALNMM
     DIVEERGMEI DLHRLPEMLG IPAIPVSARK RSGLEILMHA VAHHKEYAKP GPFIHHHSDK
     TGHKHDHHSE YAMVYNDEIE DKIDAIIEQF RKKYPDMENM RWHAIKTLEQ DETVTEQFPV
     DMSGIADRSY EKDIINQKYD FIEEVIEETL VNKNEKAEKT EHVDRYMTSK WLGLPIFLVI
     MALVFFLTFT VGDWLKGYFE TGLDLLTGAV SAGLEAAGTS PMLNSLLVDG IISGVGGILT
     FLPNIFILFL ALAFLEDSGY MARVAFVMDD IMSHLGLSGR AFLPMLLGFG CSVPAVMASR
     ALEHRKDRLK TILVTPFMSC SARLPIYVLF SSMFFGEHAM LACYSMYVLG IVVAILTAYI
     ISKIDGSKAE HALLIELPEY KAPNARTIAV YVWEKVKDYL TKAGTVIFLA SIIMWVLLNF
     GPTGYVTDIA ESFGSIIGKA IVPFFHPLGL GYWQIVVALI SGIAAKEVVV SSCSVLFGIQ
     NITTSHGMDS FVATLGAMGF GAANAYSLMV FCLLYVPCTA TIATIHREVG SKKLTCGIVL
     FQLAVAWVVS FIAYHIAGLI L
//
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