ID   A0A1Y4C166_9FIRM        Unreviewed;       371 AA.
AC   A0A1Y4C166;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=4-hydroxybutyrate dehydrogenase {ECO:0000313|EMBL:OUO40704.1};
GN   ORFNames=B5F88_07515 {ECO:0000313|EMBL:OUO40704.1};
OS   Flavonifractor sp. An306.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Flavonifractor.
OX   NCBI_TaxID=1965629 {ECO:0000313|EMBL:OUO40704.1, ECO:0000313|Proteomes:UP000195472};
RN   [1] {ECO:0000313|Proteomes:UP000195472}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=An306 {ECO:0000313|Proteomes:UP000195472};
RA   Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA   Rychlik I.;
RT   "Function of individual gut microbiota members based on whole genome
RT   sequencing of pure cultures obtained from chicken caecum.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the iron-containing alcohol dehydrogenase
CC       family. {ECO:0000256|ARBA:ARBA00007358}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUO40704.1}.
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DR   EMBL; NFIQ01000022; OUO40704.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y4C166; -.
DR   OrthoDB; 9804734at2; -.
DR   Proteomes; UP000195472; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd14860; 4HBD_NAD; 1.
DR   Gene3D; 3.40.50.1970; -; 1.
DR   Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR   InterPro; IPR001670; ADH_Fe/GldA.
DR   InterPro; IPR039697; Alcohol_dehydrogenase_Fe.
DR   PANTHER; PTHR11496; ALCOHOL DEHYDROGENASE; 1.
DR   PANTHER; PTHR11496:SF102; ALCOHOL DEHYDROGENASE 4; 1.
DR   Pfam; PF00465; Fe-ADH; 1.
DR   SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000195472}.
FT   DOMAIN          59..362
FT                   /note="Alcohol dehydrogenase iron-type/glycerol
FT                   dehydrogenase GldA"
FT                   /evidence="ECO:0000259|Pfam:PF00465"
SQ   SEQUENCE   371 AA;  40717 MW;  628E2D2735287052 CRC64;
     MVEIIFKPTL HQFRTCLEFA EEFQLTAQDL ILTNEYIYQP YFGQTNLGCH VLFQEKYGSG
     EPTDVMVDAI LADAARTGCR RVVAIGGGTV IDIAKVLAVS DGEGVDALYD KAPNLEKKRE
     LVILPTTCGT GSEVTNISIM ARTRLGTKLG LVSPAMYADH AVLIPQLLEG LPFGVFAASS
     IDALVHAVES ALSPKATPYT KLFGYKAIEM IIRGYQKIAA EGREARIPLL EDFLLASNYA
     GLAFGTAGCA AVHATSYPLG SKYHVPHGES NYAMFTGVLK AYMELKQDGE IAVMNRYLAD
     LLGCGVEAVY DKLEELLDQI LPKKPLHEYG MTKEDIDEFA HSVITSQGRL MANNFVPLDE
     DRVRRIYTEL F
//