ID A0A1Y4CM30_9BACT Unreviewed; 1912 AA.
AC A0A1Y4CM30;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=DNA methylase {ECO:0000313|EMBL:OUO44351.1};
GN ORFNames=B5F81_01060 {ECO:0000313|EMBL:OUO44351.1};
OS Muribaculum sp. An287.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Muribaculaceae;
OC Muribaculum.
OX NCBI_TaxID=1965623 {ECO:0000313|EMBL:OUO44351.1, ECO:0000313|Proteomes:UP000243574};
RN [1] {ECO:0000313|Proteomes:UP000243574}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An287 {ECO:0000313|Proteomes:UP000243574};
RA Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA Rychlik I.;
RT "Function of individual gut microbiota members based on whole genome
RT sequencing of pure cultures obtained from chicken caecum.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUO44351.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NFIX01000001; OUO44351.1; -; Genomic_DNA.
DR OrthoDB; 9815272at2; -.
DR Proteomes; UP000243574; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR003356; DNA_methylase_A-5.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR41313; ADENINE-SPECIFIC METHYLTRANSFERASE; 1.
DR PANTHER; PTHR41313:SF1; DNA METHYLASE ADENINE-SPECIFIC DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF02384; N6_Mtase; 1.
DR PRINTS; PR00507; N12N6MTFRASE.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Methyltransferase {ECO:0000313|EMBL:OUO44351.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000243574};
KW Transferase {ECO:0000313|EMBL:OUO44351.1}.
FT DOMAIN 1460..1625
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 388..428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 442..498
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 549..579
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 597..617
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1164..1191
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1660..1687
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 392..427
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 442..465
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 554..577
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1912 AA; 217759 MW; CC4B4AE2B2BAFDCB CRC64;
MAFNRKERLR GNIEAIRTAF VLDREHRAAT LEEREIISRY CGFGGLKCIL NPASSLADAV
DWAKSDLELF PMTVELHRLI RENSRNDAEY KRYMDSLKSS VLTAFYTPKE ITDTIVSVLK
KYNVTPSKVL EPSAGMGVFI LSVKEQSPHA DVMAFEKDLL TGKLLSYLYP DEKIRVEGFE
KIEKPFNGSF DLAISNVPFG EIAVFDPAFV LSDSRARVSA QRTIHNYFFL KGLDTVRDGG
VVAFLTSQGV MNSPRNEAVR LEMLKEAHLV SAVRLPNDLF TENANTEVGS DLIILQKDIR
KEGLTEDETL FTKTGTLHGV AFNSYFIKHA EQMVYTSAEL DTDPYGKPAM VYGHEGGVNG
IAEHLRRLLD HNLHANLSME MYSGSIIDKR LPDQTETVRH EPDTEKIRMP ETPESSATEE
EKPEIEAPVM TLFDLFGITA EEQRERAKPK PAKKKQTKND ENPAGESKKA SVATTSDLFR
QSDTDRDATA IPPDMEEMTE EEARQEAIYA SLDWETNPPI NGFYETMMAL GVEGRARLRQ
RIREHKAMHP ELFRQQETAS QAQTQGRQSQ QDTGEQPVYP VENGFEAEAR KHLEEVERQM
QEEEAALSPE ELEHRHKEEM QSRTFTGVME PHLKEGSLVR VDTAGVRYQI GVLKDVTRYG
ATFQPLDLDS YQKEKAALYI KVRDSYERLY AYEAEHREEH RLHRENLNTH YDEFVMRYGN
LNAGQNAKMI LMDAAGRDIL SLERGENGLF VKADIFDRPV SFSDVENVSV ETPEDALTSS
LNRYGGVNME YMCRLCGSSE AEMTESLKGR IYYNPMEDCY EIKDRFIAGN VVGKAERVGR
WMQEVRDSGM PHPMLAAAGE SLEALQKAVP SPILFDELDF NFGERWIPTG IYEAYMSYLY
DTDIKIAYVD SVDEFTVSCD RKNMKIYEQF AVKGYYKRYD GMNLLKHALH NTVPDIYKSI
GKDDKDNDIK VRDSEAIQLA NAKIDEIRSG FTEWLEAQSP EFKQRLADMY NRKFNCYVRP
MYDGSHQTFP DIDLKALGKR YGINEIYPSQ KDCVWMLKQN GGGICDHEVG TGKTLIMCMA
AHEMKRLGLA HKPMIIGLKA NVAEIAECYR TAYPNARILY ASEKDFAAAN RVKFFNSIKN
NDYDCVIMSH DQFGKIPQSP EMQQKILQAE LDTVEENLEV LKQQGKDISR AMLKGLEVRK
HNLAAKLQGI AYAIEHRTDD VADFGRMGID HIFVDESHQF KNLMFNTRHS RVAGLGNQEG
SQKALNMLYA IRTIQERTGK DLGATFLSGT TISNSLTELY LLFKYLRPKE LERQDIRCFD
AWAAIFAKKT TDFEFNVTNN IVQKERFRYF IKVPELAMFY NEITDYRTAE DVGVDRPQKN
EILYNIPPTP QQEEFIKKLM EFAKTGDATI LGREKLSESE EKAKMLIATD YARKMALDMR
LISPEYEDHP DNKASHCAKM IAEYYHKFDE QKGTQFVFSD LGTFQPGQWS VYSEIKRKLI
EDYGIPAHEI RFIQECKSEK ARKSVIAAMN EGSVRVLFGS TSMLGTGVNA QQHAIMVHHL
DTPWRPSDLQ QRDGRAVRKG NEIAKLYADN KVDVIIYAVE KSLDSYKFNL LHCKQTFINQ
LKSGAMGART IDEGAMDEKN GMNFSEYMAI LSGNTDLLDK AKLEKKIAAL EGERKSFAKA
RNEAEGKLNE KITQFANNRV IIEKMTEDYN TLLSRAETDK DGHKINRIRL DGLESTDEKR
IGTRLQEIAK NATTGGLYTR IGEVYGFPIY VISETALKDG VSAIQNRFVV EGHYKYSYNN
GQLAMADTKA AAMNFLNALE RIPQIVQQYK AKNETIERDL PVLQEVAGKT WRKEDELKSL
KSELAALDRK IRLESTMGQQ QCKCNVICPQ YMVNTVVEKE KYICKCAIKG GM
//
