ID   A0A1Y4D5Z5_9BACT        Unreviewed;       885 AA.
AC   A0A1Y4D5Z5;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   RecName: Full=Beta-galactosidase {ECO:0000256|RuleBase:RU000675};
DE            EC=3.2.1.23 {ECO:0000256|RuleBase:RU000675};
GN   ORFNames=B5F77_04590 {ECO:0000313|EMBL:OUO53882.1};
OS   Parabacteroides sp. An277.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Tannerellaceae;
OC   Parabacteroides.
OX   NCBI_TaxID=1965619 {ECO:0000313|EMBL:OUO53882.1, ECO:0000313|Proteomes:UP000196154};
RN   [1] {ECO:0000313|Proteomes:UP000196154}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=An277 {ECO:0000313|Proteomes:UP000196154};
RA   Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA   Rychlik I.;
RT   "Function of individual gut microbiota members based on whole genome
RT   sequencing of pure cultures obtained from chicken caecum.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues
CC         in beta-D-galactosides.; EC=3.2.1.23;
CC         Evidence={ECO:0000256|RuleBase:RU000675};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC       {ECO:0000256|ARBA:ARBA00009809, ECO:0000256|RuleBase:RU003679}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUO53882.1}.
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DR   EMBL; NFJB01000008; OUO53882.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y4D5Z5; -.
DR   OrthoDB; 703126at2; -.
DR   Proteomes; UP000196154; Unassembled WGS sequence.
DR   GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR   InterPro; IPR019801; Glyco_hydro_35_CS.
DR   InterPro; IPR001944; Glycoside_Hdrlase_35.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR23421:SF165; BETA-GALACTOSIDASE; 1.
DR   PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR   Pfam; PF01301; Glyco_hydro_35; 1.
DR   PRINTS; PR00742; GLHYDRLASE35.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   PROSITE; PS01182; GLYCOSYL_HYDROL_F35; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000675};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000675};
KW   Reference proteome {ECO:0000313|Proteomes:UP000196154};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..885
FT                   /note="Beta-galactosidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012960741"
FT   DOMAIN          61..391
FT                   /note="Glycoside hydrolase 35 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF01301"
SQ   SEQUENCE   885 AA;  99957 MW;  0CB14E6A9C6AB353 CRC64;
     MNKKALCCML LLAVGSASAQ YKIDLSRVEY PKIEYLKLGH PGPAGKEIRV NNLYMDEGGV
     PQLPVMGEIH YNRMDSRYWR DALLKMKASG INIVATYCIW SLHEEFEGEL SWKGNLDLRR
     FVMLCQELGL KVHLRIGPYC NAEIRNGGLP DWIVNNKNLK TRSNDPLYLA YSRRWYQAVY
     KQIEGLLYKD GGPIMALQLE NEYVKRGQII PHLTTLKKMA VEIGFDVPIY TMTHWMDSEY
     PKGEIVPYAG FYIEAPWTAH GKEEIPTGNF EFFTYNRLSD NIGTDIIKMD GEVESLSGEN
     NDSPFFTCEI GVGTTAFYGR RAVVPEEMAG EMINLRLGCG ANLMGYYMYA GGTNPVGEAT
     TTQSSGPRVC YDYQAPVREY GTLGKVMPEV KKYNYFMNDF GTALAPAVAY LPTSNQDREN
     LQWAVRSDGT KGYLFCSNYL YKHERNDFKN VQFTVKLKDE TFRMPRKKTT VKGGTYFFWP
     FNQNLDDVLL KYATTQPVCS LEEGKDMTYF FFEDDGIPGE YAIAGEGIKN VTVSKGVCQK
     EKKGYFVNQL EAGTDCVIEI TKADGQKVRF VTLTEEESDQ LWKGEIRGKE FVALSTSSLI
     VDKDEMTLID NAPQAEISFY KGGKFQERNF QGGARSLKAT YHSLAPLAES EWIMPSEGKD
     VERSFTLHTF SDVERAYLHY ASTGNASCAI NGKEIQAHQA GDYWLADVTS QINTKENRVV
     FAVANQPIAA ELEILLKNGE RIVWNTDATW LTSETKTPVR IVTSPGKKPA AFAPEEHLAL
     YKVNIPRAKG GEEETRMYIQ YQGDVANLYQ NGQLVADSYY DGTDWIVSVD RLKEAADVNP
     IIIRIDGLKS ADAPIYFEKN VNPADCVYPK ISGIEVKQEY RFKVK
//