ID A0A1Y4DBJ6_9BACT Unreviewed; 363 AA.
AC A0A1Y4DBJ6;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=isochorismate synthase {ECO:0000256|ARBA:ARBA00012824};
DE EC=5.4.4.2 {ECO:0000256|ARBA:ARBA00012824};
DE AltName: Full=Isochorismate mutase {ECO:0000256|ARBA:ARBA00041564};
GN ORFNames=B5F77_07375 {ECO:0000313|EMBL:OUO52901.1};
OS Parabacteroides sp. An277.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Tannerellaceae;
OC Parabacteroides.
OX NCBI_TaxID=1965619 {ECO:0000313|EMBL:OUO52901.1, ECO:0000313|Proteomes:UP000196154};
RN [1] {ECO:0000313|Proteomes:UP000196154}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An277 {ECO:0000313|Proteomes:UP000196154};
RA Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA Rychlik I.;
RT "Function of individual gut microbiota members based on whole genome
RT sequencing of pure cultures obtained from chicken caecum.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=chorismate = isochorismate; Xref=Rhea:RHEA:18985,
CC ChEBI:CHEBI:29748, ChEBI:CHEBI:29780; EC=5.4.4.2;
CC Evidence={ECO:0000256|ARBA:ARBA00000799};
CC -!- SIMILARITY: Belongs to the isochorismate synthase family.
CC {ECO:0000256|ARBA:ARBA00005297}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUO52901.1}.
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DR EMBL; NFJB01000014; OUO52901.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y4DBJ6; -.
DR OrthoDB; 9806579at2; -.
DR Proteomes; UP000196154; Unassembled WGS sequence.
DR GO; GO:0008909; F:isochorismate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR InterPro; IPR005801; ADC_synthase.
DR InterPro; IPR015890; Chorismate_C.
DR InterPro; IPR004561; IsoChor_synthase.
DR NCBIfam; TIGR00543; isochor_syn; 1.
DR PANTHER; PTHR42839; ISOCHORISMATE SYNTHASE ENTC; 1.
DR PANTHER; PTHR42839:SF2; ISOCHORISMATE SYNTHASE ENTC; 1.
DR Pfam; PF00425; Chorismate_bind; 1.
DR SUPFAM; SSF56322; ADC synthase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000196154}.
FT DOMAIN 109..354
FT /note="Chorismate-utilising enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00425"
SQ SEQUENCE 363 AA; 41647 MW; 0DBE6E2E86075E8E CRC64;
MIREENEFVI DQLIQEGRSF ALWRIPGEET IHFRMQTTGS PDLIYDLSAL NGRSGFVIAP
FHVSTEHPIV LIQPDCFELP EKTKASSPEN IGMFARKEYD VSDKAKAWNQ YQVAFQHFWS
ALDAKKAEKL VLSRSFTWEK AERLSPGKAF FRACRHYIYS YVYLCHTPQT GTWIGGTPEI
LLAGEGTQWQ TIALAGTQHL VDGQLPKPWD EKNMREQQLV ATYIREQLEK KGIHPEEQGP
YSAVAVELAH LRSDFRFELP DTQHLGDLLD LLHPTPAVCG FPKEIAHRFI LEREGYDRSY
YSGFVGWLSP VGRTDLYVNL RCATMQDHCY TLFAGGGLLP SSRLQEEWQE TNDKMQTMKK
IIE
//
