ID A0A1Y4DDA3_9BACT Unreviewed; 555 AA.
AC A0A1Y4DDA3;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=B5F77_00290 {ECO:0000313|EMBL:OUO55699.1};
OS Parabacteroides sp. An277.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Tannerellaceae;
OC Parabacteroides.
OX NCBI_TaxID=1965619 {ECO:0000313|EMBL:OUO55699.1, ECO:0000313|Proteomes:UP000196154};
RN [1] {ECO:0000313|Proteomes:UP000196154}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An277 {ECO:0000313|Proteomes:UP000196154};
RA Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA Rychlik I.;
RT "Function of individual gut microbiota members based on whole genome
RT sequencing of pure cultures obtained from chicken caecum.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUO55699.1}.
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DR EMBL; NFJB01000001; OUO55699.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y4DDA3; -.
DR Proteomes; UP000196154; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06563; GH20_chitobiase-like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000196154}.
FT DOMAIN 31..161
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 164..507
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 338
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 555 AA; 63228 MW; 16E8411C679BC5A5 CRC64;
MMKTRLRQFA GAAFLLVLTG CSSPTVEVGN LKVIPLPQEV FQPMTEKPFV MNARTVVYCQ
PDNEALVRTA HFVVSYVKEL TGIEMEVVDK RPSSNVIVLS VSNNAKGKDA YRMDVAENRV
LIEGGSEAGV FYGVQTLYKA LPIVKGTEKV AALPAGLIDD APRFPYRGFM IDVGRHYFPV
SYLKEMIDLM AMHNINYFHW HLTEDQGWRI EIKKYPKLTE IGSVRDSTLI DPVTREYDGV
PHSGFYTQDE AREIVRYAAE RFITVIPEID MPGHMMAALA SYPELGCTGG PYTIPGRFGV
HKEVLCAGNP KTLQFAKDVL EEIMDIFPSP YIHIGGDECP KKRWRECPKC QAKIRELGIK
ETPEHTKENQ LQTYFMGEIE KFVNEHGRQI LGWDEILEGG LTPNATVVSW RGTEGGIAAA
RQHHPVIMAP IQYLYFSNPR WNKIPGVNSV KRVYCFEPVP KELTPDEQQF VIGVQGCLWT
EWTKDSLKME WQLLPRMAAL SEIQWTEPDK KDFESFKKRL PAMLEKYTVR GYHYREDIHD
TTIVELPVDS VLYHD
//
