ID   A0A1Y4DH17_9ACTN        Unreviewed;       312 AA.
AC   A0A1Y4DH17;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   13-SEP-2023, entry version 19.
DE   RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN   ORFNames=B5F74_10650 {ECO:0000313|EMBL:OUO58225.1};
OS   Collinsella sp. An271.
OC   Bacteria; Actinomycetota; Coriobacteriia; Coriobacteriales;
OC   Coriobacteriaceae; Collinsella.
OX   NCBI_TaxID=1965616 {ECO:0000313|EMBL:OUO58225.1, ECO:0000313|Proteomes:UP000195889};
RN   [1] {ECO:0000313|Proteomes:UP000195889}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=An271 {ECO:0000313|Proteomes:UP000195889};
RA   Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA   Rychlik I.;
RT   "Function of individual gut microbiota members based on whole genome
RT   sequencing of pure cultures obtained from chicken caecum.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUO58225.1}.
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DR   EMBL; NFJE01000014; OUO58225.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y4DH17; -.
DR   OrthoDB; 4961576at2; -.
DR   Proteomes; UP000195889; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   Pfam; PF13676; TIR_2; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   PROSITE; PS50104; TIR; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000195889}.
FT   DOMAIN          1..125
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
SQ   SEQUENCE   312 AA;  34418 MW;  A9698623C223CDC6 CRC64;
     MKIFISHTAA DKSVVEPAAL ALSRAFGRDN VFYDSWSIQP GDGIIDKMNS GLEDCDCFFL
     FVSERSLTSE MVKMEWQNAL MIHAKRGMRF VPVLLDDCKV PAIFLQKRYI DAFRAGMDVA
     IRQMIDVASG ANIYHEEDAT FQNLKAYARL SKGSGVDIEV RAEMMMEPIS EYAVVLESDS
     ASVTCPGEVF YRSGKGGPIE NDRGMKCIPY IVAIDRPTVK GFPFRIRVED EASISVQGVF
     HAAGEGRFER VPVVVVMPDD VFHFGADIEV PLDDVCAPGI TQEDQLAALN KIMSEALSKS
     EPHGESNKDN GA
//