ID   A0A1Y4EMH2_9FIRM        Unreviewed;       815 AA.
AC   A0A1Y4EMH2;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=PAS domain S-box protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=B5F54_14485 {ECO:0000313|EMBL:OUO72666.1};
OS   Anaeromassilibacillus sp. An250.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Anaeromassilibacillus.
OX   NCBI_TaxID=1965604 {ECO:0000313|EMBL:OUO72666.1, ECO:0000313|Proteomes:UP000195568};
RN   [1] {ECO:0000313|Proteomes:UP000195568}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=An250 {ECO:0000313|Proteomes:UP000195568};
RA   Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA   Rychlik I.;
RT   "Function of individual gut microbiota members based on whole genome
RT   sequencing of pure cultures obtained from chicken caecum.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUO72666.1}.
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DR   EMBL; NFJK01000019; OUO72666.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y4EMH2; -.
DR   Proteomes; UP000195568; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 2.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 3.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013655; PAS_fold_3.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 2.
DR   PANTHER; PTHR46663; DIGUANYLATE CYCLASE DGCT-RELATED; 1.
DR   PANTHER; PTHR46663:SF2; GGDEF DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF08447; PAS_3; 2.
DR   Pfam; PF13426; PAS_9; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00086; PAC; 2.
DR   SMART; SM00091; PAS; 3.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50113; PAC; 2.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   Reference proteome {ECO:0000313|Proteomes:UP000195568}.
FT   DOMAIN          87..136
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          139..190
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          268..320
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          351..489
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
SQ   SEQUENCE   815 AA;  93873 MW;  2EF4FF29F0479301 CRC64;
     MARDGIAGYF LHPAGHLFSD PAAIHFHARK KLLMVSESFK MSGGTKMVDN RSIRPTELPA
     QPGLVRLMCD GIPGGIFRCL PDPVWTILEV SRGFLNLFGY TAEEMREKFH NHYLDMIHPH
     DRRAVTRAFQ KHMETGTDHC LEYRVKHRDG HTLWILEQSH LMQRDGEPDT LCCTLTDITE
     GKKLQEQLRL SLERHQILMD QTDDIIIEWN METDSFFCSP KWETKFGYMP QREHITRHIL
     HGDSHIHPED RQRVAEALRS IRRGALHSDL EFRICTADGR YLWCRARMTV QTSQANHPVH
     AIGLLVDIDS EKRQAEKLLE IAQRDPLTNL LNKVASQKRI EEYLNTAADG DCSALLIVDL
     DNFKHINDSM GHLVGDAILV DAAQRLKTHF RSTDTVGRLG GDEFIIHIQN IQDVSIVQKK
     AEQLILELGD IETVNNGMEN SPSIALSCSI GAAIYPKHGK SFKELYRHAD LALYQSKKNG
     KNQYNVYDGS YQQERILRPY TQPASIPEEK VDADGPGNLL DYLSEHCFHI LYHSRDVETA
     VQSILEMVGK KFNVSRSYIF EDSEDGSYCR NTFEWCNEGI SPQIDNLRCI SYEKDLNNRY
     RDNFNEEGIF YCRDIRLLEE EPYAILAPQG IKALLQSAIY DNGVFRGFVG FDDCSINRFW
     TQDQVDALAF ISEILSVFLL KHRAQQRTVQ AEESIRSILE NQSTWIYLID PKSYELLYVN
     RCLGQIFPSA QIGMHCYEAF FRRDHPCTEC LFRKLTEKNQ SLLQEVYHAA LDLWLMTDTS
     MVTWHNRPAV LMCCFDITPY KKAGTNDLLD KNLRP
//