ID A0A1Y4EWH8_9FIRM Unreviewed; 955 AA.
AC A0A1Y4EWH8;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=SH3b domain-containing protein {ECO:0000259|PROSITE:PS51781};
GN ORFNames=B5F54_02605 {ECO:0000313|EMBL:OUO75833.1};
OS Anaeromassilibacillus sp. An250.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Anaeromassilibacillus.
OX NCBI_TaxID=1965604 {ECO:0000313|EMBL:OUO75833.1, ECO:0000313|Proteomes:UP000195568};
RN [1] {ECO:0000313|Proteomes:UP000195568}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An250 {ECO:0000313|Proteomes:UP000195568};
RA Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA Rychlik I.;
RT "Function of individual gut microbiota members based on whole genome
RT sequencing of pure cultures obtained from chicken caecum.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUO75833.1}.
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DR EMBL; NFJK01000002; OUO75833.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y4EWH8; -.
DR Proteomes; UP000195568; Unassembled WGS sequence.
DR GO; GO:0003796; F:lysozyme activity; IEA:InterPro.
DR GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR Gene3D; 1.10.530.40; -; 1.
DR Gene3D; 2.60.40.1080; -; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 7.
DR InterPro; IPR003343; Big_2.
DR InterPro; IPR008964; Invasin/intimin_cell_adhesion.
DR InterPro; IPR023346; Lysozyme-like_dom_sf.
DR InterPro; IPR023347; Lysozyme_dom_sf.
DR InterPro; IPR003646; SH3-like_bac-type.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR PANTHER; PTHR34408; FAMILY PROTEIN, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR34408:SF1; GLYCOSYL HYDROLASE FAMILY 19 DOMAIN-CONTAINING PROTEIN HI_1415; 1.
DR Pfam; PF02368; Big_2; 1.
DR Pfam; PF08239; SH3_3; 7.
DR SMART; SM00635; BID_2; 1.
DR SMART; SM00287; SH3b; 7.
DR SUPFAM; SSF49373; Invasin/intimin cell-adhesion fragments; 1.
DR SUPFAM; SSF53955; Lysozyme-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51781; SH3B; 6.
PE 4: Predicted;
KW Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW Antimicrobial {ECO:0000256|ARBA:ARBA00022529};
KW Bacteriolytic enzyme {ECO:0000256|ARBA:ARBA00022638};
KW Reference proteome {ECO:0000313|Proteomes:UP000195568};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..955
FT /note="SH3b domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012621702"
FT DOMAIN 26..89
FT /note="SH3b"
FT /evidence="ECO:0000259|PROSITE:PS51781"
FT DOMAIN 102..165
FT /note="SH3b"
FT /evidence="ECO:0000259|PROSITE:PS51781"
FT DOMAIN 174..244
FT /note="SH3b"
FT /evidence="ECO:0000259|PROSITE:PS51781"
FT DOMAIN 257..324
FT /note="SH3b"
FT /evidence="ECO:0000259|PROSITE:PS51781"
FT DOMAIN 428..492
FT /note="SH3b"
FT /evidence="ECO:0000259|PROSITE:PS51781"
FT DOMAIN 817..884
FT /note="SH3b"
FT /evidence="ECO:0000259|PROSITE:PS51781"
FT REGION 325..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..350
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 955 AA; 99791 MW; D631F0375A25B6A2 CRC64;
MGSAAAALLC TVSLAVTALP TGAWAASTAQ TTDYLNLRTG AGQSYSVLLT MPKGTEVTIL
DDSQGEWAKV RLASGQEGYC SKEYLTAVGS LSTATYGALA TGDTAVTTAN LNVRKGVGTS
YGIVTTLAEG ASVTILDSSH ATWAKVRTAS GLEGYCLKEY LSGSAATGGS SSSTGSGTST
GMTAVTQDYL NLRTGPGTNY DRVLTLAQGV SVSVLDNSNA EWVKVRTTSG QEGYCSRQYL
TISGSSSGGN TGSSSSGTSG EIIATVKENL NLREGAGPSY AIIKTMQQGD TVTVIDNSHP
TWARVRTADG TVGCCSKEFL DIQANSASGT PSDPSDAAGG SSTANESLPA TAKESVAMRT
GAGTSYEVIR ALFPQENVTV TDNSHATWAK IRTSDGTEGY CMKQYLDIQT ASTGTDPGTG
NTGDGQTITG ATVTADALRL RSGPGTQYDQ VATLLKGATL TVLDTSNAGW TKVQTANNLT
GYVSNEYIQF LYNGQTGVSA DALTISRTSG TVSAGKTLYI KATANPSTAS VTWSSSNTAV
ATVTNGYIYG VSPGTAVITA TSGSQPKTCT VTVTAAEPVR TAYASPNIAG VGSAVTFTAI
TDTTRDGVRF TVQFPSGTTQ MISATSSTTE TTGQTSTKVW KAAMNLTEQG TYRVTVSSSQ
GGVYSAESFE TSAYVVSSQD YTVTTSEQRR ASDKMIELIA NWEGYSASVY ADKLTSTQVP
TLGYGLTLKE GDTFYNDLSK TEAWSLLVNT VNSASYTTEV NKFITQNNLL MSQCQFDSLV
SFGYNVGAGY WNSTSSEIDL RRIILNAVVP PQDFGTGMSA TISKATVVRS TPSLSGTQVC
EAEKGTAITV TSANFSNQKD GWYLATLPNG STGWINSGYV TLNGANLVHD LNYTNAYAFG
TDMLRWNQAG GKSYAGLLYR RLGEANVYNY NDYSASRVNT YGYTYPAALA YLDTQ
//
