ID A0A1Y4F497_9FIRM Unreviewed; 391 AA.
AC A0A1Y4F497;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Alanyl-tRNA editing protein {ECO:0000313|EMBL:OUO76438.1};
GN ORFNames=B5F53_17050 {ECO:0000313|EMBL:OUO76438.1};
OS Blautia sp. An249.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Blautia.
OX NCBI_TaxID=1965603 {ECO:0000313|EMBL:OUO76438.1, ECO:0000313|Proteomes:UP000195974};
RN [1] {ECO:0000313|Proteomes:UP000195974}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An249 {ECO:0000313|Proteomes:UP000195974};
RA Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA Rychlik I.;
RT "Function of individual gut microbiota members based on whole genome
RT sequencing of pure cultures obtained from chicken caecum.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUO76438.1}.
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DR EMBL; NFJL01000025; OUO76438.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y4F497; -.
DR OrthoDB; 9812949at2; -.
DR Proteomes; UP000195974; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004813; F:alanine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0002161; F:aminoacyl-tRNA editing activity; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006419; P:alanyl-tRNA aminoacylation; IEA:InterPro.
DR Gene3D; 2.40.30.130; -; 1.
DR Gene3D; 3.10.310.40; -; 1.
DR InterPro; IPR018165; Ala-tRNA-synth_IIc_core.
DR InterPro; IPR018164; Ala-tRNA-synth_IIc_N.
DR InterPro; IPR003156; DHHA1_dom.
DR InterPro; IPR018163; Thr/Ala-tRNA-synth_IIc_edit.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR012947; tRNA_SAD.
DR PANTHER; PTHR43462; ALANYL-TRNA EDITING PROTEIN; 1.
DR PANTHER; PTHR43462:SF1; ALANYL-TRNA EDITING PROTEIN AARSD1; 1.
DR Pfam; PF02272; DHHA1; 1.
DR Pfam; PF01411; tRNA-synt_2c; 1.
DR Pfam; PF07973; tRNA_SAD; 1.
DR SMART; SM00863; tRNA_SAD; 1.
DR SUPFAM; SSF55186; ThrRS/AlaRS common domain; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS50860; AA_TRNA_LIGASE_II_ALA; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000195974}.
FT DOMAIN 1..235
FT /note="Alanyl-transfer RNA synthetases family profile"
FT /evidence="ECO:0000259|PROSITE:PS50860"
SQ SEQUENCE 391 AA; 44246 MW; 151479016E7D4FF2 CRC64;
MTEQLYYQNV YLRECTAMVR TCYKEKDRYA AVLDRTVFYP EGGGQPYDTG TLGDAKVLEV
HKKDGEIVHY LDRPLEEGKE VTAEINWERR FDLMQQHSGE HMVSGIVHEK YGYDNVGFHM
GSDVITIDFN GILTEEQLGE VENLVNQKVW ENRNVEITYP SEEELRTLPY RSKKELTGEI
RIVNIPETDL CACCGLHVTH TGEVGMVKLL SVQKFRQGVR VEMICGNRVL SYLNEINTQN
KEISVLLSAH PAKTAAAVKR LWEENFQNKG KVISLEERVF QNEAESLKGA GNTLIWEEGL
ESDSVRKLTD AVMHTCQGLC AVFSEQKDGS FKYAVGEEGG DLRTFIKEMN QALQGKGGGK
PFFAQGFVQA SKEEIEEFFR KLSPTVCGSK K
//
