ID A0A1Y4F6D4_9FIRM Unreviewed; 380 AA.
AC A0A1Y4F6D4;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=ROK family transcriptional regulator {ECO:0008006|Google:ProtNLM};
GN ORFNames=B5F53_09365 {ECO:0000313|EMBL:OUO78875.1};
OS Blautia sp. An249.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Blautia.
OX NCBI_TaxID=1965603 {ECO:0000313|EMBL:OUO78875.1, ECO:0000313|Proteomes:UP000195974};
RN [1] {ECO:0000313|Proteomes:UP000195974}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An249 {ECO:0000313|Proteomes:UP000195974};
RA Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA Rychlik I.;
RT "Function of individual gut microbiota members based on whole genome
RT sequencing of pure cultures obtained from chicken caecum.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transcriptional repressor of xylose-utilizing enzymes.
CC {ECO:0000256|ARBA:ARBA00002486}.
CC -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC {ECO:0000256|ARBA:ARBA00006479}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUO78875.1}.
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DR EMBL; NFJL01000008; OUO78875.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y4F6D4; -.
DR OrthoDB; 9796533at2; -.
DR Proteomes; UP000195974; Unassembled WGS sequence.
DR CDD; cd00090; HTH_ARSR; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011991; ArsR-like_HTH.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000600; ROK.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR18964:SF177; N-ACETYLMANNOSAMINE KINASE; 1.
DR PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR Pfam; PF13412; HTH_24; 1.
DR Pfam; PF00480; ROK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS01125; ROK; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000195974}.
SQ SEQUENCE 380 AA; 41715 MW; 1A9973345B8D484D CRC64;
MITGSKELIR NLNTRLVIRT VLKEGPISRA ALASRVGLTK ATISSIVQSL LDAGLLIEIG
NEQTKKGRKP ILLKLNADCG HILSIDLSPE YITLLTSNLA GEHCALKRTE NHTDRETILP
RLISLITQSL AVLPPSPYGL VGISLGLHGV VHENRPVFIP YSPYSGIDFA AALQEKFHCP
VQLENEANLS VLGEHAFAFS CENLVNISVH AGIGLGIYMK GQLLKGQDGY AGEFGHSIIQ
IRGRQCPCGN RGCLEQYASE TALLKELSQK KGRQISIEEF AVLYQKKDAD ALSTADDFVT
YLSVGVNNIL QILNPEMIVI NSAFTMYFPQ LCQQITDCLA NSMKKHCRLV PSRLQDTAIL
LGGVTLIRDY FLEHTERLPL
//
