ID   A0A1Y4FD47_9FIRM        Unreviewed;       432 AA.
AC   A0A1Y4FD47;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=PDZ domain-containing protein {ECO:0000259|PROSITE:PS50106};
GN   ORFNames=B5F53_03615 {ECO:0000313|EMBL:OUO80802.1};
OS   Blautia sp. An249.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Blautia.
OX   NCBI_TaxID=1965603 {ECO:0000313|EMBL:OUO80802.1, ECO:0000313|Proteomes:UP000195974};
RN   [1] {ECO:0000313|Proteomes:UP000195974}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=An249 {ECO:0000313|Proteomes:UP000195974};
RA   Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA   Rychlik I.;
RT   "Function of individual gut microbiota members based on whole genome
RT   sequencing of pure cultures obtained from chicken caecum.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase S1C family.
CC       {ECO:0000256|ARBA:ARBA00010541}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUO80802.1}.
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DR   EMBL; NFJL01000002; OUO80802.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y4FD47; -.
DR   OrthoDB; 1765023at2; -.
DR   Proteomes; UP000195974; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd00987; PDZ_serine_protease; 1.
DR   Gene3D; 2.30.42.10; -; 1.
DR   Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR041489; PDZ_6.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR   InterPro; IPR001940; Peptidase_S1C.
DR   PANTHER; PTHR22939:SF125; PROTEASE DO-LIKE 14-RELATED; 1.
DR   PANTHER; PTHR22939; SERINE PROTEASE FAMILY S1C HTRA-RELATED; 1.
DR   Pfam; PF17820; PDZ_6; 1.
DR   Pfam; PF13365; Trypsin_2; 1.
DR   PRINTS; PR00834; PROTEASES2C.
DR   SMART; SM00228; PDZ; 1.
DR   SUPFAM; SSF50156; PDZ domain-like; 1.
DR   SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR   PROSITE; PS50106; PDZ; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000195974};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        37..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          326..414
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   REGION          72..108
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   432 AA;  47777 MW;  98A86217CA73EB69 CRC64;
     MQWKKKKEGN ENPENYYFIK ETIKKNGKKE RILKTGYLLG AGILFGLAAA AAFTLAAPQF
     LQINEENAEK TQKVQIPVDS PQEQEETEEN AQVQEQEKPE AASSAQTEKN ALEQYESAYQ
     EILTIAEKPQ KALVTVYGES EDENLLDKTR LTYGLASGII YMENENEYYI LTETKAVENA
     ETLWVTFQDG KTVKGNPRKS DPRTGLAVMT VEKEKIPQDT RAGLYVASLG NSYSLFRGKG
     VIALGNPSAY SDLVSYGVIT SVANEYQSID ARYNLLMTDI LGEEQSSGVL LNNQGEIIGL
     IVQPQEGQNA SSSMVKALAV SQLKPLLEIL SNGETIMYLG IKGEEVDESS QSRGIPQGIY
     VDSVERDSPA MKAGVQSGDI ICSLNGEPVA TMQEYSTYLQ KCKEGQKIKV VLKRRGTENY
     EKMEYTMIVE GI
//