ID A0A1Y4FE44_9FIRM Unreviewed; 577 AA.
AC A0A1Y4FE44;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=FHA domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=B5F53_05585 {ECO:0000313|EMBL:OUO79928.1};
OS Blautia sp. An249.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Blautia.
OX NCBI_TaxID=1965603 {ECO:0000313|EMBL:OUO79928.1, ECO:0000313|Proteomes:UP000195974};
RN [1] {ECO:0000313|Proteomes:UP000195974}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An249 {ECO:0000313|Proteomes:UP000195974};
RA Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA Rychlik I.;
RT "Function of individual gut microbiota members based on whole genome
RT sequencing of pure cultures obtained from chicken caecum.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUO79928.1}.
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DR EMBL; NFJL01000004; OUO79928.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y4FE44; -.
DR OrthoDB; 9816434at2; -.
DR Proteomes; UP000195974; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00060; FHA; 1.
DR CDD; cd00198; vWFA; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 2.60.40.1220; -; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR014755; Cu-Rt/internalin_Ig-like.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR23308:SF53; KANADAPTIN-RELATED; 1.
DR PANTHER; PTHR23308; NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF00092; VWA; 1.
DR SMART; SM00240; FHA; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000195974};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 417..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 88..267
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 499..549
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
SQ SEQUENCE 577 AA; 63704 MW; D7C7DBE411693ED1 CRC64;
MVNRGIRILT AVLLMLTGIF LVPQASYGAS ASDVRMEQVS VCMPQVKVYL MGEDVQDVDF
QQITAQKEDE ELSVESIGDF GDSGEGILYM CLLDISGSID AESFQGAKDA LLDFAGQLKD
TEKCMLLTFG NDVKTVWVGS ESQEERKKLL DGIQNDNENT QLFEALHQAA DLSVENKGSI
DRKVALVFTD GLDEAVGKST SQEALNELQA KGLPVYGIAV GKEKKTEAVN SFGEFVRSSG
GALTVPESTA VSQDLIQLKE QLYQARVLGM KGSSNLVSKE VETVKLTFQQ YPKTESLKTE
VTEYEKDTEA PQIEDVVQLS DNQIQVIFTE AMNGIDEAEN FQLIDKKEKS LVPEASSVEE
KRIATLTFKD NFYRGDYTLE FKNITDYSME KNPLEDTANL TLEGDLNLKI VSFLKSWGWL
LAIVLVAAAA ATAIIIYRKI KKNKGLVVID DKLTLQDQVQ VEKRQKVEFK DVPGAALQIQ
LRSGTSAGAV IERFLSDSLI VGRSSQLCGL CIQDSRMSKQ HFVLEFEKGR IFITDLESTN
GTMVNGVRLL GRQPLNPGDL ICAGNMEMVI QWQEKNG
//
