ID   A0A1Y4GCG2_9BACT        Unreviewed;       470 AA.
AC   A0A1Y4GCG2;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Glutamate synthase (NADPH), homotetrameric {ECO:0000313|EMBL:OUO91598.1};
GN   ORFNames=B5F39_12705 {ECO:0000313|EMBL:OUO91598.1};
OS   Cloacibacillus sp. An23.
OC   Bacteria; Synergistota; Synergistia; Synergistales; Synergistaceae;
OC   Cloacibacillus.
OX   NCBI_TaxID=1965591 {ECO:0000313|EMBL:OUO91598.1, ECO:0000313|Proteomes:UP000196418};
RN   [1] {ECO:0000313|Proteomes:UP000196418}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=An23 {ECO:0000313|Proteomes:UP000196418};
RA   Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA   Rychlik I.;
RT   "Function of individual gut microbiota members based on whole genome
RT   sequencing of pure cultures obtained from chicken caecum.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUO91598.1}.
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DR   EMBL; NFJQ01000013; OUO91598.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y4GCG2; -.
DR   OrthoDB; 9803192at2; -.
DR   Proteomes; UP000196418; Unassembled WGS sequence.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR028261; DPD_II.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR009051; Helical_ferredxn.
DR   InterPro; IPR006004; SudA-like.
DR   NCBIfam; TIGR01316; gltA; 1.
DR   PANTHER; PTHR43100; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR   PANTHER; PTHR43100:SF1; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR   Pfam; PF14691; Fer4_20; 1.
DR   Pfam; PF07992; Pyr_redox_2; 2.
DR   PRINTS; PR00419; ADXRDTASE.
DR   SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR   SUPFAM; SSF51971; Nucleotide-binding domain; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000196418}.
FT   DOMAIN          20..131
FT                   /note="Dihydroprymidine dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF14691"
FT   DOMAIN          141..222
FT                   /note="FAD/NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF07992"
FT   DOMAIN          228..452
FT                   /note="FAD/NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF07992"
SQ   SEQUENCE   470 AA;  50680 MW;  68A49F9FF06041BE CRC64;
     MAVTFSKWKT PIKEQDPEIR RSNFGEVCLG YTLEEGRTEA GRCLQCKTKP CVAGCPVKID
     IPAFIKCIKE GDMAGAAAIM DQYTNLPAVC GRVCPQESQC EGKCTVGKMK DFEPVAIGKL
     ERLVADWKYA QENMEAKPYE GEKKGRVAVV GSGPSSLTVA GDLAKMGYEV KIFEALHAAG
     GVLIYGIPEF RLPKKIVKME IEAMQKLGVD IETNVVVGKT ITMQEIMQEY DACYIAVGAG
     APHFQGVPGT TLNGVYSASE YLTRINLMHG YEFPKFDTPA KKAHKVVVIG GGNVAMDAAR
     SAKRLGAEEV TVVYRRSLAE LPARIEEYHH AVEEGIVFNW LTNPTEYVDD GNGSLKGVKC
     IKMELGEPDA SGRRRPVPVE GSEFFIEADC AIEAIGQGSN KVLLSTFPEM KLNKWGYIEA
     DPVTGATSVP GVFAGGDIVT GAATVILAMG AGKEAAVAID KYITEKKAAK
//