ID A0A1Y4H8W5_9FIRM Unreviewed; 408 AA.
AC A0A1Y4H8W5;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Alanyl-transfer RNA synthetases family profile domain-containing protein {ECO:0000259|PROSITE:PS50860};
GN ORFNames=B5F36_04615 {ECO:0000313|EMBL:OUP04454.1};
OS Anaerofilum sp. An201.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Anaerofilum.
OX NCBI_TaxID=1965588 {ECO:0000313|EMBL:OUP04454.1, ECO:0000313|Proteomes:UP000195817};
RN [1] {ECO:0000313|Proteomes:UP000195817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An201 {ECO:0000313|Proteomes:UP000195817};
RA Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA Rychlik I.;
RT "Function of individual gut microbiota members based on whole genome
RT sequencing of pure cultures obtained from chicken caecum.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUP04454.1}.
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DR EMBL; NFJT01000005; OUP04454.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y4H8W5; -.
DR OrthoDB; 9812949at2; -.
DR Proteomes; UP000195817; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004813; F:alanine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0002161; F:aminoacyl-tRNA editing activity; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006419; P:alanyl-tRNA aminoacylation; IEA:InterPro.
DR Gene3D; 2.40.30.130; -; 1.
DR InterPro; IPR018165; Ala-tRNA-synth_IIc_core.
DR InterPro; IPR018163; Thr/Ala-tRNA-synth_IIc_edit.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR012947; tRNA_SAD.
DR PANTHER; PTHR43462; ALANYL-TRNA EDITING PROTEIN; 1.
DR PANTHER; PTHR43462:SF1; ALANYL-TRNA EDITING PROTEIN AARSD1; 1.
DR Pfam; PF07973; tRNA_SAD; 1.
DR SMART; SM00863; tRNA_SAD; 1.
DR SUPFAM; SSF55186; ThrRS/AlaRS common domain; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS50860; AA_TRNA_LIGASE_II_ALA; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000195817}.
FT DOMAIN 20..238
FT /note="Alanyl-transfer RNA synthetases family profile"
FT /evidence="ECO:0000259|PROSITE:PS50860"
SQ SEQUENCE 408 AA; 43511 MW; F8D2E7EE2007198B CRC64;
MTKDPKTATQ RRRAPVCAPQ KLYYQNSLLL SFSAVVTACE AAGEGKWKAA LTATAFYPEG
GGQPADHGTL GGARVLDVHE KEGEIWHTLD APLPVGETVE GTVDAARRLD LMQQHTGEHI
LSGTLHRMFG AENVGFHISP DTLTMDTSCE ISAEGLAEAE REANRTIWND TPVRCWWPDK
EELAATAYRS KKALEGPVRL VDIPGADCCA CCGTHLPTAG MVGSIKIIAH ERYKGGTRLT
VVCGARALAD HADKCAQTAR IGARLSAKPV AVADAVDRLA AENADLKARL AAAETGWVGQ
LAAAVQPQDA PLAVAALSPD GVRRLALAMS ERTGRPCLAA APEEGRMRYA LVWQDDRLPA
LNRRLTDALH GRGGGRPPLA MGSFAADEAA LRALWSEINQ QIQEGTPL
//
