ID   A0A1Y4HB80_9FIRM        Unreviewed;       633 AA.
AC   A0A1Y4HB80;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Topoisomerase {ECO:0000313|EMBL:OUP04706.1};
GN   ORFNames=B5F36_04330 {ECO:0000313|EMBL:OUP04706.1};
OS   Anaerofilum sp. An201.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Anaerofilum.
OX   NCBI_TaxID=1965588 {ECO:0000313|EMBL:OUP04706.1, ECO:0000313|Proteomes:UP000195817};
RN   [1] {ECO:0000313|Proteomes:UP000195817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=An201 {ECO:0000313|Proteomes:UP000195817};
RA   Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA   Rychlik I.;
RT   "Function of individual gut microbiota members based on whole genome
RT   sequencing of pure cultures obtained from chicken caecum.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUP04706.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; NFJT01000004; OUP04706.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y4HB80; -.
DR   OrthoDB; 9802530at2; -.
DR   Proteomes; UP000195817; Unassembled WGS sequence.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   Gene3D; 3.40.1360.10; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.90.580.10; Zinc finger, CHC2-type domain; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR036977; DNA_primase_Znf_CHC2.
DR   InterPro; IPR025054; DUF3991.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF13481; AAA_25; 1.
DR   Pfam; PF13154; DUF3991; 1.
DR   Pfam; PF13155; Toprim_2; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF56731; DNA primase core; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF57783; Zinc beta-ribbon; 1.
PE   4: Predicted;
KW   Isomerase {ECO:0000313|EMBL:OUP04706.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000195817}.
FT   DOMAIN          331..506
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   REGION          82..111
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   633 AA;  70649 MW;  6670C4B8F8EB995F CRC64;
     MYYTQEQIDR ANQADLVLFL QSQGEPLERA GQEYRWKRHD SLTVRGNKWY RHSQSKGGGP
     IDFVMEFFGK SFTEAVELLT GEKGAAPPPD RPSSAPLSDF RLPPRSPDNR TARNYLTAAR
     RIDEDVTGFF FASGDIYEDA AHHNAVFVGR DEDGIPRYAH SKGTAGNFRL DVKGSDKAFN
     FCYRGEGERV FVFEAPVDLL SFLCLFKKDW QKQSYLSLGG VGEKALLRFL SDRPNIKTVY
     LCLDSDEAGN DACSRLVKLM PEGYTVHRLI PLFKDWNEVL QHRAEITDGK YLREAVYGLK
     EPPQEETVEI IRMSEVDTQT VEWLWEPYIP FGKVTIVQGN PGEGKTTFAL RLAAACTNRK
     PFPHMAVHEP FNVIYQTAED GLGDTIKPRL MEAEADLDRI LVIDESKQGL SLSDERIERA
     IRQTGARLII LDPIQAYVGE KTDMNKANEI RPMFRRLAEI AERTGCAVIL IGHLNKAAGG
     QSAYRGLGSI DFRAAARSVL LIGRVKREPN VRVIVHDKSS LAPEGKPIAF CLDPETGFSW
     IGEYDITADE LLSGAGGNTA TKTEQAERLI LDLLADGKEL ASEDLVKAAA EAGISERTVQ
     NAKRNMGGVL GARRVDGQWY NFIKKKQPPE PAS
//