ID   A0A1Y4IBP3_9FIRM        Unreviewed;       469 AA.
AC   A0A1Y4IBP3;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Uracil permease {ECO:0000313|EMBL:OUP17653.1};
GN   ORFNames=B5F29_13585 {ECO:0000313|EMBL:OUP17653.1};
OS   Lachnoclostridium sp. An196.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1965583 {ECO:0000313|EMBL:OUP17653.1, ECO:0000313|Proteomes:UP000199780};
RN   [1] {ECO:0000313|Proteomes:UP000199780}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=An196 {ECO:0000313|Proteomes:UP000199780};
RA   Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA   Rychlik I.;
RT   "Function of individual gut microbiota members based on whole genome
RT   sequencing of pure cultures obtained from chicken caecum.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC       2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUP17653.1}.
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DR   EMBL; NFJZ01000012; OUP17653.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y4IBP3; -.
DR   OrthoDB; 9805749at2; -.
DR   Proteomes; UP000199780; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR   GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR   InterPro; IPR006043; NCS2.
DR   InterPro; IPR006042; Xan_ur_permease.
DR   NCBIfam; NF037981; NCS2_1; 1.
DR   PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR   PANTHER; PTHR42810:SF2; PURINE PERMEASE C1399.01C-RELATED; 1.
DR   Pfam; PF00860; Xan_ur_permease; 1.
DR   PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199780};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        38..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        70..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        99..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        122..143
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        155..176
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        188..208
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        215..237
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        272..301
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        351..373
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        379..397
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        409..430
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        442..461
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   469 AA;  50062 MW;  8F81A19BCA93F740 CRC64;
     MDYRNIEEKV TTVSTENIYK LNGRVPLSKA IPFGMQHVLA MFVANLAPVL IVCSAALVRG
     TGENLTSAEI TQLLQCAMFA AGIGTCMQLY PIWKIGSRLP IVMGVSFTFL GSLLIICTNP
     ELGYEGMIGA VILGGIFEGL VGLSAKYWKR FLTPVVSACV VIAIGLSLLS VGMDSWGGGS
     GVEDFGAWYH LLIGAFTLVV CLVSRYLLKG VYKNLNILVG LIAGYLVSVL FTVTGVAQMV
     DFSNISRTIE EVGIFSIPKL VFFTSHKPVF DLGAFFTIAI VFLVSAAETT GATTAVCTGA
     LGRDIKIEEL QGSLAVDGFS SAISGCFGCL PLTSFSQNVG LVTMTRVVNR FTILMGALIL
     ILASLFPPLG AFFNSLPQSV LGGCTVMMFG SIMYEGIKML KECEFDDRTM TIVSLAFCIG
     VGLTQTSGNF FSAFPREVGD IFNGNAVAGV FVVSLLLSLL LPKKEHSEK
//