ID   A0A1Y4IE87_9FIRM        Unreviewed;       569 AA.
AC   A0A1Y4IE87;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Sensor histidine kinase {ECO:0000313|EMBL:OUP18638.1};
GN   ORFNames=B5F29_10115 {ECO:0000313|EMBL:OUP18638.1};
OS   Lachnoclostridium sp. An196.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1965583 {ECO:0000313|EMBL:OUP18638.1, ECO:0000313|Proteomes:UP000199780};
RN   [1] {ECO:0000313|Proteomes:UP000199780}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=An196 {ECO:0000313|Proteomes:UP000199780};
RA   Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA   Rychlik I.;
RT   "Function of individual gut microbiota members based on whole genome
RT   sequencing of pure cultures obtained from chicken caecum.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUP18638.1}.
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DR   EMBL; NFJZ01000008; OUP18638.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y4IE87; -.
DR   OrthoDB; 9809348at2; -.
DR   Proteomes; UP000199780; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR   PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR   PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR   Pfam; PF06580; His_kinase; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:OUP18638.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199780};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        284..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          311..363
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
SQ   SEQUENCE   569 AA;  65577 MW;  6D51FFEBB06629F9 CRC64;
     MKSPRLPSLS HKLFLTFILS FIVPLILIDF FISYLFSDYQ YQGLHAQSEN NTQLISAYMA
     NYINDIDDIM KGLYFNSYLQ SETDISALSI YDKSRLSEEI GDTLSLTAYS RDDFGDLLFI
     SEQEVLYFNA ENYYQYLPTT QSLEDRSWYL AALKKDGKIA ITPYQDPKNV ESAQNADSFF
     VSRQLKNLHD PDQENVIMIN LKTSFLDTLF SKLDANTPGI VLFTNDDGEL IYSSQDIDDA
     FLNHLGSSPF RYGGRIWIQD SQPLENYPLT IHVLLSTSYV VQQFATFMLI CVVGFLVAIC
     IAYLLFRGNN RWIQMPVHRI QSVLKTMEKG GLDARCPDLP IREFQDIGSS VNHMAEKLQE
     KIHNEYELLI AQKNLQFQAL QSQIRPHFII NTIYSFITLN QIGETELLND CFYRFANILR
     YVLSKDQETT LEKELDFLDS YCSLFHLRFG DRIQYHISCE DPLRPLKMPK LLLQPLVENA
     VIHGIEPSEI PCTLDISVEK HGEKIYIIIE DSGVGFQKDQ LFSSTSIGLK NVENRIQLWN
     KDIEFYIYRA EGLTIQAVII PDSVQEAKQ
//