ID A0A1Y4IHP9_9FIRM Unreviewed; 637 AA.
AC A0A1Y4IHP9;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Sensor histidine kinase NatK C-terminal domain-containing protein {ECO:0000259|Pfam:PF14501};
GN ORFNames=B5F29_07555 {ECO:0000313|EMBL:OUP19828.1};
OS Lachnoclostridium sp. An196.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1965583 {ECO:0000313|EMBL:OUP19828.1, ECO:0000313|Proteomes:UP000199780};
RN [1] {ECO:0000313|Proteomes:UP000199780}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An196 {ECO:0000313|Proteomes:UP000199780};
RA Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA Rychlik I.;
RT "Function of individual gut microbiota members based on whole genome
RT sequencing of pure cultures obtained from chicken caecum.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUP19828.1}.
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DR EMBL; NFJZ01000005; OUP19828.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y4IHP9; -.
DR OrthoDB; 9156435at2; -.
DR Proteomes; UP000199780; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR CDD; cd16935; HATPase_AgrC-ComD-like; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR032834; NatK_C.
DR Pfam; PF14501; HATPase_c_5; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199780};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 212..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 263..283
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 361..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 393..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 530..631
FT /note="Sensor histidine kinase NatK C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14501"
SQ SEQUENCE 637 AA; 72897 MW; CC0C0C4E581AC843 CRC64;
MMVHRGIRLV FWVILSFLLS SAVCITLYFL NNKYTDPAPQ AENGYLDLTQ ETEETYPLRF
LRDGWAFYPD TLLGPEDFND GAPKEYMVYT SIGDFTRFDR MGTRETPFGC GTWVLDLWLP
ETGDYALELP EIFSAYRFYV NDRLVLQTGD PDPETYTPKT QIRTVHLNDS GHVRLILAVS
NYTHFYSGMV YPPAFGTLQA VFHYRIMQSL SAASWDIFIL ILFGLMLGAA FRMHHTNALL
FAALCLAAVG YTSYPLIHLF KLSIFPWYGL EIFCGYLLIF LAVTIQNRIC MPPRVCICVS
QTVSLAFSLL ALAYGMLSPV LTVSVMQTFS WFSAAVKLLA TAYLLAASFW GIFQRHPESR
ILLYGNTAYS AFFLWDRLLP VYEPVYGGWF PELGIQILVV FIFCALAADI LRAYSFHQSF
AESYRQLSRQ LAIQKAHYQE LTSQIEETVR IRHDQRHHLT VISTLLEEGR LSQAQKYLSE
YQSRLHFKER TVLCRCLMVD TILQYYKKLC EQNHIHFTVQ AELPPELPFS DTDLTILFGN
LVENAYEACL SSDSAAPSIH LKTAYEHQKF YLRVENTFSN KIHTVNGKYL SGKHDGTGIG
TESVRAVVKR LDGQIRFQTL SDHFQVSVIL PAEQKIL
//
