ID A0A1Y4ITZ6_9FIRM Unreviewed; 618 AA.
AC A0A1Y4ITZ6;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Nucleoside-diphosphate sugar epimerase {ECO:0000313|EMBL:OUP22400.1};
GN ORFNames=B5F29_01270 {ECO:0000313|EMBL:OUP22400.1};
OS Lachnoclostridium sp. An196.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1965583 {ECO:0000313|EMBL:OUP22400.1, ECO:0000313|Proteomes:UP000199780};
RN [1] {ECO:0000313|Proteomes:UP000199780}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An196 {ECO:0000313|Proteomes:UP000199780};
RA Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA Rychlik I.;
RT "Function of individual gut microbiota members based on whole genome
RT sequencing of pure cultures obtained from chicken caecum.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC {ECO:0000256|ARBA:ARBA00007430}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUP22400.1}.
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DR EMBL; NFJZ01000001; OUP22400.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y4ITZ6; -.
DR OrthoDB; 9803111at2; -.
DR Proteomes; UP000199780; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003869; Polysac_CapD-like.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR Pfam; PF13727; CoA_binding_3; 1.
DR Pfam; PF02719; Polysacc_synt_2; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199780};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 54..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 112..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 293..573
FT /note="Polysaccharide biosynthesis protein CapD-like"
FT /evidence="ECO:0000259|Pfam:PF02719"
SQ SEQUENCE 618 AA; 70141 MW; 0D4835BFA14DC4BF CRC64;
MFKNRSKKMT YRIILLILVD MLIITLSGPL AIYVRYNLFF EARAIEFIEN IFRYLPINLI
ITIGTFYVFR LYQGIWKYAS ASDLVNIIVA CLVSAVTQSV GMWLMHLDYP RSYPFMYFFI
LTFGISVFRF MYRILGYVQQ KKEGLIRTGK KNTMIVGAGE AGNTLLKELQ NSRFSEQYVC
CLVDDDPGKQ GKYLRGVPVE GTRNDICRLA EEYDIDEIMI AIPSAPHGEI QELLDICSQT
SCKLKVLPGL YQLANGEVSI SKLRNVEIED LLGREPIDTK IDSIMDYVSG KTVLVTGGGG
SIGSELCRQI ARHEPKRLII LDIYENNAYD IQQELKHDYP KLDLTVLIGS VRNTHRVNSI
FEKYRPDIVY HAAAHKHVPL MEDSPNEAIK NNVFGTYKTA KAADRYGTLR FVLISTDKAV
NPTNIMGASK RLCEMIIQMM NDCSKTEFVA VRFGNVLGSN GSVIPLFKKQ IEEGGPVTVT
DPNIIRYFMT IPEAVSLVLQ AGAFAKGGEI FVLDMGKPVK ILDLALNLIR LSGYKPYEDI
DIQFTGLRPG EKLYEELLMD EEGLQSTKNK LIHIGKPIEF DEKLFLHQLE ELDRLSREDN
PHIKDKVAEI VTTYHRKD
//
