ID   A0A1Y4IV46_9FIRM        Unreviewed;       288 AA.
AC   A0A1Y4IV46;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:OUP24214.1};
GN   ORFNames=B5F28_07350 {ECO:0000313|EMBL:OUP24214.1};
OS   Gemmiger sp. An194.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Gemmiger.
OX   NCBI_TaxID=1965582 {ECO:0000313|EMBL:OUP24214.1, ECO:0000313|Proteomes:UP000196090};
RN   [1] {ECO:0000313|Proteomes:UP000196090}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=An194 {ECO:0000313|Proteomes:UP000196090};
RA   Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA   Rychlik I.;
RT   "Function of individual gut microbiota members based on whole genome
RT   sequencing of pure cultures obtained from chicken caecum.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUP24214.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; NFKA01000009; OUP24214.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y4IV46; -.
DR   OrthoDB; 9802008at2; -.
DR   Proteomes; UP000196090; Unassembled WGS sequence.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR   GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR046825; PDH_C.
DR   InterPro; IPR046826; PDH_N.
DR   InterPro; IPR003099; Prephen_DH.
DR   PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR   Pfam; PF20463; PDH_C; 1.
DR   Pfam; PF02153; PDH_N; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS51176; PDH_ADH; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000196090}.
FT   DOMAIN          5..288
FT                   /note="Prephenate/arogenate dehydrogenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51176"
SQ   SEQUENCE   288 AA;  31802 MW;  D4BDBA7619A9F683 CRC64;
     MNKDDRFLIV GLGLLGGSYA RGLTRAGFGE VYAIDTNPEA IRFAQDKGYI RDGATENFEE
     LVRAADRVIF ALYPTALEGW VARYGALLRP GCLCTDVSGV KAGLVETVQA ALPEGVEFIA
     SHPMAGKEVS GVENAHLVDF SPANFLITPT ERNTPEGVEF ARQLGQALGF AHIRVLSCAE
     HDRMIGYVSQ LTHAIAVSLM CAPGAERFAE YTGDSFRDLT RIARINETMW AELFLWNREN
     LIDEIDGFSA RLQALKGYLQ QGDRAALEEM FRQSTRARAA FDKKEKEE
//