ID A0A1Y4IWI0_9FIRM Unreviewed; 735 AA.
AC A0A1Y4IWI0;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=GGDEF domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=B5F28_05770 {ECO:0000313|EMBL:OUP24717.1};
OS Gemmiger sp. An194.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Gemmiger.
OX NCBI_TaxID=1965582 {ECO:0000313|EMBL:OUP24717.1, ECO:0000313|Proteomes:UP000196090};
RN [1] {ECO:0000313|Proteomes:UP000196090}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An194 {ECO:0000313|Proteomes:UP000196090};
RA Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA Rychlik I.;
RT "Function of individual gut microbiota members based on whole genome
RT sequencing of pure cultures obtained from chicken caecum.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUP24717.1}.
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DR EMBL; NFKA01000006; OUP24717.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y4IWI0; -.
DR OrthoDB; 9762141at2; -.
DR Proteomes; UP000196090; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd18774; PDC2_HK_sensor; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF84; SIGNALLING PROTEIN WITH EAL DOMAIN; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000196090};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 346..478
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 484..735
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 735 AA; 82994 MW; A25583D2FB8C6F0F CRC64;
MKRFEKNRKT ILFLCYLPMI LFIGLLWNAA SRQIHSQLFS TLADLARQNR YVVSYSINQK
MEELERVAQG LAQREDFPQG VAIDDLATVA NVLGFREIGV TGLDGMARMS TDTSYDITGR
EYFQMSVQGF NWVSKTLCDM RDGKKVNVCS VPVRSDSGAV IGTLLGTIET DEFFASMQVP
SFHEQGYAYV VNQDGDVVLT TRSDGVEVTN FCTLLYQNPG NVDQLNQLRD CLAGKTESVN
LLVNEDERHY INVSWLGYDD LWLVTGVPEH ALDSGIMTQF KVIQVLSVVF AVAGLAGLFF
LNLIMDRNDR HLRKLAYVDA RTGIHNHFYL RETMGEFTTL GPGKGKRVAV LLFNIQQFKN
INNLYGSVAG DQVLKHVAQH LSAVFGEGRT LARDTADSFV VLSPYEDWNQ LLEQAETLCA
DLPLLPFNNN EIGVKLRCGI YRLPDGVQPD EEALFRARMA CFEAPRESGV GVYCAQVQQK
MERKKEQQNT IRQAIANREF KAWLQPKFCA QTRSLLGAEA LARWCRPDGS VLPPGAFIAD
CEEMGIIGEV DEMVLEDVCR QIRDWREQGI QCPPVSVNLS RVYLSSLDIV DKIDRVLNRY
KLERQAIQLE ITESALVKDE DGLRDVVERM RSLGFTIVLD DFGKGYSSLS SIHDLRFDII
KIDKSFVDRI GSEQGDQMIR FIIELARALQ LELVAEGVED QSQYEFLRGL GCHAIQGYYF
SKPLSCQDFA DQYLQ
//
