ID   A0A1Y4K186_9ACTN        Unreviewed;       290 AA.
AC   A0A1Y4K186;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   13-SEP-2023, entry version 18.
DE   RecName: Full=cyclic pyranopterin monophosphate synthase {ECO:0000256|ARBA:ARBA00012575};
DE            EC=4.6.1.17 {ECO:0000256|ARBA:ARBA00012575};
GN   ORFNames=B5F23_06080 {ECO:0000313|EMBL:OUP38574.1};
OS   Olsenella sp. An188.
OC   Bacteria; Actinomycetota; Coriobacteriia; Coriobacteriales; Atopobiaceae;
OC   Olsenella.
OX   NCBI_TaxID=1965579 {ECO:0000313|EMBL:OUP38574.1, ECO:0000313|Proteomes:UP000196278};
RN   [1] {ECO:0000313|Proteomes:UP000196278}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=An188 {ECO:0000313|Proteomes:UP000196278};
RA   Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA   Rychlik I.;
RT   "Function of individual gut microbiota members based on whole genome
RT   sequencing of pure cultures obtained from chicken caecum.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic
CC         pyranopterin phosphate + diphosphate; Xref=Rhea:RHEA:49580,
CC         ChEBI:CHEBI:33019, ChEBI:CHEBI:59648, ChEBI:CHEBI:131766;
CC         EC=4.6.1.17; Evidence={ECO:0000256|ARBA:ARBA00001637};
CC   -!- PATHWAY: Cofactor biosynthesis; molybdopterin biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00005046}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUP38574.1}.
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DR   EMBL; NFKF01000004; OUP38574.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y4K186; -.
DR   OrthoDB; 9794429at2; -.
DR   UniPathway; UPA00344; -.
DR   Proteomes; UP000196278; Unassembled WGS sequence.
DR   GO; GO:0061799; F:cyclic pyranopterin monophosphate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030151; F:molybdenum ion binding; IEA:InterPro.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.
DR   CDD; cd01420; MoaC_PE; 1.
DR   Gene3D; 3.30.70.640; Molybdopterin cofactor biosynthesis C (MoaC) domain; 1.
DR   Gene3D; 2.40.33.20; PK beta-barrel domain-like; 1.
DR   InterPro; IPR023045; MoaC.
DR   InterPro; IPR047594; MoaC_bact/euk.
DR   InterPro; IPR036522; MoaC_sf.
DR   InterPro; IPR005302; MoCF_Sase_C.
DR   InterPro; IPR002820; Mopterin_CF_biosynth-C_dom.
DR   InterPro; IPR011037; Pyrv_Knase-like_insert_dom_sf.
DR   NCBIfam; TIGR00581; moaC; 1.
DR   PANTHER; PTHR36930; METAL-SULFUR CLUSTER BIOSYNTHESIS PROTEINS YUAD-RELATED; 1.
DR   PANTHER; PTHR36930:SF1; MOSC DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF01967; MoaC; 1.
DR   Pfam; PF03473; MOSC; 1.
DR   SUPFAM; SSF55040; Molybdenum cofactor biosynthesis protein C, MoaC; 1.
DR   SUPFAM; SSF50800; PK beta-barrel domain-like; 1.
DR   PROSITE; PS51340; MOSC; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Molybdenum cofactor biosynthesis {ECO:0000256|ARBA:ARBA00023150}.
FT   DOMAIN          164..288
FT                   /note="MOSC"
FT                   /evidence="ECO:0000259|PROSITE:PS51340"
SQ   SEQUENCE   290 AA;  30248 MW;  7E74DFEC70088ABB CRC64;
     MVDVSAKPAT DRVARAAGFV RMAPSTVGLV RTGGAKKGDV LAVAQVAGIM AAKRCWELVP
     MCHPVQLTGV DVRFSVGEGG VGIEATCRCH GETGVEMEAL TAVSAAALTV YDMLKAHQRD
     MVIEDVRLVE KRGGASGDYA AGAARGAATV EAVCVSEEKG TRKRPVDAIE LVVGEGVSGD
     AHAGNWHRQV SLLPAEAVDE LRDRLPDLAP GDFAENILTR GVDLKALPVG TVLRAGAAEL
     VVTQIGKECH TACEIRRLTG RCAMPTEGIF CVVTRGGTVR AGDSLEVVAR
//