ID   A0A1Y4NDA6_9FIRM        Unreviewed;       634 AA.
AC   A0A1Y4NDA6;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Nucleoside-diphosphate sugar epimerase {ECO:0000313|EMBL:OUP78824.1};
GN   ORFNames=B5F09_01325 {ECO:0000313|EMBL:OUP78824.1};
OS   Erysipelatoclostridium sp. An173.
OC   Bacteria; Bacillota; Erysipelotrichia; Erysipelotrichales;
OC   Coprobacillaceae; Thomasclavelia.
OX   NCBI_TaxID=1965571 {ECO:0000313|EMBL:OUP78824.1, ECO:0000313|Proteomes:UP000196550};
RN   [1] {ECO:0000313|Proteomes:UP000196550}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=An173 {ECO:0000313|Proteomes:UP000196550};
RA   Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA   Rychlik I.;
RT   "Function of individual gut microbiota members based on whole genome
RT   sequencing of pure cultures obtained from chicken caecum.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC       {ECO:0000256|ARBA:ARBA00007430}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUP78824.1}.
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DR   EMBL; NFKR01000002; OUP78824.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y4NDA6; -.
DR   Proteomes; UP000196550; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003869; Polysac_CapD-like.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR   PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR   Pfam; PF13727; CoA_binding_3; 1.
DR   Pfam; PF02719; Polysacc_synt_2; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000196550};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        46..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        108..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          289..569
FT                   /note="Polysaccharide biosynthesis protein CapD-like"
FT                   /evidence="ECO:0000259|Pfam:PF02719"
SQ   SEQUENCE   634 AA;  71869 MW;  E7556D35FE3EF209 CRC64;
     MGEKTKLNAR RFLLVGLDII SILIAAYGSL FLRFNGPIDP MFLSRLNNII ILLVLIDISI
     FVCFRLYHSL WQFASITELK NIIIAAFTNC IINTVVCELT GNGQPKSCYI IFFLMLVLMV
     GGTRFLYRFI RMYKQHVIAE KERRPLEKVL IVGAGVAGEK VLREINNSNH IYKEVVCFID
     DEPSKWKRQI HGVDIYGGRN KIIEAVEKYG VSEILVAMPS ISKKELANIL NICKETRCQI
     KRLPGIYQFI NDDIHISDFK DVEVQDLLGR EPIKVNLDDI MGYVTGKVVM VTGGGGSIGS
     ELCRQIAANK PETLIIVDIY ENNAYDIQLE LRRKYPDLHL ETMIASVRNS VKVDKLFETY
     HPDIVYHAAA HKHVPLMEDS PNEAVKNNVF GTLNVVKAAD KYKTKRFILI STDKAVNPTN
     IMGATKRLCE MIVQTYNKKS KTEYVAVRFG NVLGSNGSVI PLFKKQIKEG GPVTVTHPDI
     IRYFMTIPEA VSLVLQAGAY AKGGEIFVLD MGEPVKIADM ARNLIKLSGY EPDVDIDIVY
     TGLRPGEKLY EELLMEEEGL QDTPNHMIHI GKPIELDEES FFEDLKELKE EAYEEVDDIR
     ILVKKMVPTY HYNVKTNKTP IVKEVERPKE TVEV
//