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Database: UniProt
Entry: A0A1Y4NEA3_9FIRM
LinkDB: A0A1Y4NEA3_9FIRM
Original site: A0A1Y4NEA3_9FIRM 
ID   A0A1Y4NEA3_9FIRM        Unreviewed;       125 AA.
AC   A0A1Y4NEA3;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   RecName: Full=Manganese transport regulator {ECO:0000256|ARBA:ARBA00032593};
GN   ORFNames=B5F09_00875 {ECO:0000313|EMBL:OUP79163.1};
OS   Erysipelatoclostridium sp. An173.
OC   Bacteria; Bacillota; Erysipelotrichia; Erysipelotrichales;
OC   Coprobacillaceae; Thomasclavelia.
OX   NCBI_TaxID=1965571 {ECO:0000313|EMBL:OUP79163.1, ECO:0000313|Proteomes:UP000196550};
RN   [1] {ECO:0000313|Proteomes:UP000196550}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=An173 {ECO:0000313|Proteomes:UP000196550};
RA   Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA   Rychlik I.;
RT   "Function of individual gut microbiota members based on whole genome
RT   sequencing of pure cultures obtained from chicken caecum.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the DtxR/MntR family.
CC       {ECO:0000256|ARBA:ARBA00007871}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUP79163.1}.
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DR   EMBL; NFKR01000001; OUP79163.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y4NEA3; -.
DR   Proteomes; UP000196550; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0046914; F:transition metal ion binding; IEA:InterPro.
DR   Gene3D; 1.10.60.10; Iron dependent repressor, metal binding and dimerisation domain; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR001367; Fe_dep_repressor.
DR   InterPro; IPR036421; Fe_dep_repressor_sf.
DR   InterPro; IPR022687; HTH_DTXR.
DR   InterPro; IPR022689; Iron_dep_repressor.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR33238; IRON (METAL) DEPENDENT REPRESSOR, DTXR FAMILY; 1.
DR   PANTHER; PTHR33238:SF7; TRANSCRIPTIONAL REGULATOR MNTR; 1.
DR   Pfam; PF02742; Fe_dep_repr_C; 1.
DR   Pfam; PF01325; Fe_dep_repress; 1.
DR   SMART; SM00529; HTH_DTXR; 1.
DR   SUPFAM; SSF47979; Iron-dependent repressor protein, dimerization domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50944; HTH_DTXR; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000196550};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          1..65
FT                   /note="HTH dtxR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50944"
SQ   SEQUENCE   125 AA;  14275 MW;  271D92284AF5BC14 CRC64;
     MEEMTIAMQN YLELIYELSL DGKKARVSDI AKRLGVSKPS VNNAVVVLSK NGYVNYEKYS
     DIKLTPKGIE MAEFFSNKHQ TIKKLFIEVL NIDEEIADKD ACLIEHVISD ESIKAMQAYL
     KNRDE
//
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