ID   A0A1Y4NEJ9_9FIRM        Unreviewed;       453 AA.
AC   A0A1Y4NEJ9;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   RecName: Full=Citrate synthase {ECO:0000256|PIRNR:PIRNR001369};
GN   ORFNames=B5F08_05260 {ECO:0000313|EMBL:OUP79273.1};
OS   Anaeromassilibacillus sp. An172.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Anaeromassilibacillus.
OX   NCBI_TaxID=1965570 {ECO:0000313|EMBL:OUP79273.1, ECO:0000313|Proteomes:UP000195869};
RN   [1] {ECO:0000313|Proteomes:UP000195869}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=An172 {ECO:0000313|Proteomes:UP000195869};
RA   Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA   Rychlik I.;
RT   "Function of individual gut microbiota members based on whole genome
RT   sequencing of pure cultures obtained from chicken caecum.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+);
CC         Xref=Rhea:RHEA:16845, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16452, ChEBI:CHEBI:16947, ChEBI:CHEBI:57287,
CC         ChEBI:CHEBI:57288; EC=2.3.3.16;
CC         Evidence={ECO:0000256|ARBA:ARBA00000308};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle.
CC       {ECO:0000256|ARBA:ARBA00005163}.
CC   -!- SIMILARITY: Belongs to the citrate synthase family.
CC       {ECO:0000256|ARBA:ARBA00010566, ECO:0000256|PIRNR:PIRNR001369}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUP79273.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; NFKS01000008; OUP79273.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y4NEJ9; -.
DR   OrthoDB; 9800864at2; -.
DR   UniPathway; UPA00223; -.
DR   Proteomes; UP000195869; Unassembled WGS sequence.
DR   GO; GO:0036440; F:citrate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniPathway.
DR   CDD; cd06113; citrate_synt_like_1_2; 1.
DR   Gene3D; 1.10.580.10; Citrate Synthase, domain 1; 1.
DR   Gene3D; 1.10.230.10; Cytochrome P450-Terp, domain 2; 1.
DR   InterPro; IPR016142; Citrate_synth-like_lrg_a-sub.
DR   InterPro; IPR016143; Citrate_synth-like_sm_a-sub.
DR   InterPro; IPR002020; Citrate_synthase.
DR   InterPro; IPR024176; Citrate_synthase_bac-typ.
DR   InterPro; IPR036969; Citrate_synthase_sf.
DR   PANTHER; PTHR11739; CITRATE SYNTHASE; 1.
DR   PANTHER; PTHR11739:SF4; CITRATE SYNTHASE, PEROXISOMAL; 1.
DR   Pfam; PF00285; Citrate_synt; 1.
DR   PIRSF; PIRSF001369; Citrate_synth; 1.
DR   PRINTS; PR00143; CITRTSNTHASE.
DR   SUPFAM; SSF48256; Citrate synthase; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000195869};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001369}.
FT   ACT_SITE        331
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001369-1"
FT   ACT_SITE        390
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001369-1"
SQ   SEQUENCE   453 AA;  50930 MW;  8DAF1DFE6F4CAF21 CRC64;
     MIFDYSDNNP QIMSLADICL ANNNIDQSLY TKYDVKRGLR DLDGKGVLAG LTDISEIRQN
     KIVDGKTVPT DGKLFYRGIN VNDIIKGFLK DKRFGFEEVT YLLIFGKLPN AQELEEFTNL
     LATYRTLPTN FVRDVVMKAP TSDMMNTLAR SVLTLYCYDK NANDISISNV LRQCLQLISV
     FPLLSVYGYQ AYNHYCCNQS LVIHVPDPKL STAENILMLL REDKKYTELE AKVLDLALVL
     HAEHGGGNNS TFTTHVVTSS GTDTYSAIAA ALSSLKGPKH GGANLKVVGM FEEMKREIKD
     WTDEEEIDVY LQKLLHKEAF DRSGLIYGMG HAVYSISDPR AIALKSFVKE LAVEKGLEKE
     FTLYSNVERL APIVIGREKK IYKGVSANVD FYSGFIYSML GLPKELFTPI FAIARISGWS
     AHRLEELINA GKIIRPAYKS VCDEKEYIPL SER
//