ID A0A1Y4NK68_9FIRM Unreviewed; 388 AA.
AC A0A1Y4NK68;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Site-specific integrase {ECO:0000313|EMBL:OUP80461.1};
GN ORFNames=B5F08_00990 {ECO:0000313|EMBL:OUP80461.1};
OS Anaeromassilibacillus sp. An172.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Anaeromassilibacillus.
OX NCBI_TaxID=1965570 {ECO:0000313|EMBL:OUP80461.1, ECO:0000313|Proteomes:UP000195869};
RN [1] {ECO:0000313|Proteomes:UP000195869}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An172 {ECO:0000313|Proteomes:UP000195869};
RA Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA Rychlik I.;
RT "Function of individual gut microbiota members based on whole genome
RT sequencing of pure cultures obtained from chicken caecum.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Site-specific tyrosine recombinase, which acts by catalyzing
CC the cutting and rejoining of the recombining DNA molecules.
CC {ECO:0000256|ARBA:ARBA00003283}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC {ECO:0000256|ARBA:ARBA00008857}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUP80461.1}.
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DR EMBL; NFKS01000001; OUP80461.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y4NK68; -.
DR OrthoDB; 9785687at2; -.
DR Proteomes; UP000195869; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR CDD; cd01189; INT_ICEBs1_C_like; 1.
DR Gene3D; 1.10.150.130; -; 1.
DR Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR InterPro; IPR044068; CB.
DR InterPro; IPR011010; DNA_brk_join_enz.
DR InterPro; IPR013762; Integrase-like_cat_sf.
DR InterPro; IPR002104; Integrase_catalytic.
DR InterPro; IPR010998; Integrase_recombinase_N.
DR InterPro; IPR004107; Integrase_SAM-like_N.
DR PANTHER; PTHR30629; PROPHAGE INTEGRASE; 1.
DR PANTHER; PTHR30629:SF2; PROPHAGE INTEGRASE INTS-RELATED; 1.
DR Pfam; PF14659; Phage_int_SAM_3; 1.
DR Pfam; PF00589; Phage_integrase; 1.
DR SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR PROSITE; PS51900; CB; 1.
DR PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE 3: Inferred from homology;
KW DNA integration {ECO:0000256|ARBA:ARBA00022908};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01248}; Reference proteome {ECO:0000313|Proteomes:UP000195869};
KW Virus entry into host cell {ECO:0000256|ARBA:ARBA00023296}.
FT DOMAIN 66..149
FT /note="Core-binding (CB)"
FT /evidence="ECO:0000259|PROSITE:PS51900"
FT DOMAIN 169..374
FT /note="Tyr recombinase"
FT /evidence="ECO:0000259|PROSITE:PS51898"
SQ SEQUENCE 388 AA; 44221 MW; 94ED12E6F368D4D8 CRC64;
MVAGHLQEKK GYFYMVLSYP DAAGKRKTKW LPTGLPVKGN KKKAEKMLME TRQTFVPECK
PIQEDMLFSD FLLQWLEIAK PTIALTTYAS YSGMAKSVII PYFKEREITL SEMKATDIQA
FYMKQLKRVK ANTVIHYHSV IHRALKYAVK IDLISVNPAD KVERPKADKF IGSFYDSNEV
QALFEAAKGT LIEIPIFLGA FYGLRRSEAL GLKWDAIDFQ NNTITIRHTV TSCNLDGKHI
QIAQDTTKTK SSMRTLPLVP AFKEKLLKLK EQQEEYRRVC GRCYNKKYLE YICVDEMGTL
ISPHYLTASF PKLLEKNNLR HIRFHDLRHS CASLLLANGV PMKQIQEWLG HSDFSTTANV
YAHLDYNSKL SSADAMVNGL SGALEVIS
//
