ID A0A1Y4NWN1_9FIRM Unreviewed; 388 AA.
AC A0A1Y4NWN1;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=RNA methyltransferase {ECO:0000313|EMBL:OUP85224.1};
GN ORFNames=B5F07_05645 {ECO:0000313|EMBL:OUP85224.1};
OS Lachnoclostridium sp. An169.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1965569 {ECO:0000313|EMBL:OUP85224.1, ECO:0000313|Proteomes:UP000195962};
RN [1] {ECO:0000313|Proteomes:UP000195962}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An169 {ECO:0000313|Proteomes:UP000195962};
RA Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA Rychlik I.;
RT "Function of individual gut microbiota members based on whole genome
RT sequencing of pure cultures obtained from chicken caecum.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUP85224.1}.
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DR EMBL; NFKT01000005; OUP85224.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y4NWN1; -.
DR OrthoDB; 9809404at2; -.
DR Proteomes; UP000195962; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0034470; P:ncRNA processing; IEA:UniProt.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR PANTHER; PTHR47313; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L; 1.
DR PANTHER; PTHR47313:SF1; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS01261; UPF0020; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:OUP85224.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000195962};
KW Transferase {ECO:0000313|EMBL:OUP85224.1}.
FT DOMAIN 197..208
FT /note="UPF0020"
FT /evidence="ECO:0000259|PROSITE:PS01261"
SQ SEQUENCE 388 AA; 44577 MW; 6B20A765EA54DD6B CRC64;
MEKTEWIAPC HFGLESVLKR EIQDLGYEIV QVEDGRVTFR GGMEAGCRAN VFLRTAERIL
LKVGSFRAVT FEELFERTKA IPWEDYIPKD GKFWVAKAAS VKSRLFSPSD IQSIMKKAMV
ERLKGVYHMQ WFEESGASYP LRVFLKKDTV TVGLDTTGVS LHKRGYRPAA GKAPIAENLA
AALIMLTPWK KDRILVDPFC GSGTFPIEAA MMAANIAPGM NRNFTAENWT NLMDRKLWYS
AVDEAQDLID DRVETDIQGY DIDGDVIRTA RRNAQEAGVD HLIHFQQRAV KDLSHPKKYG
FIITNPPYGE RLEEKEALPR LYREFGESFR RLDSWSAYMI TSYEEAERYF GRKADKNRKI
YNGMLKTYFY QFSGPRPPRQ KKTEGTEK
//
