ID   A0A1Y4NXW7_9FIRM        Unreviewed;       542 AA.
AC   A0A1Y4NXW7;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Na/Pi-cotransporter {ECO:0000313|EMBL:OUP85656.1};
GN   ORFNames=B5F07_02975 {ECO:0000313|EMBL:OUP85656.1};
OS   Lachnoclostridium sp. An169.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1965569 {ECO:0000313|EMBL:OUP85656.1, ECO:0000313|Proteomes:UP000195962};
RN   [1] {ECO:0000313|Proteomes:UP000195962}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=An169 {ECO:0000313|Proteomes:UP000195962};
RA   Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA   Rychlik I.;
RT   "Function of individual gut microbiota members based on whole genome
RT   sequencing of pure cultures obtained from chicken caecum.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUP85656.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; NFKT01000003; OUP85656.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y4NXW7; -.
DR   OrthoDB; 9763003at2; -.
DR   Proteomes; UP000195962; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005436; F:sodium:phosphate symporter activity; IEA:InterPro.
DR   GO; GO:0044341; P:sodium-dependent phosphate transport; IEA:InterPro.
DR   InterPro; IPR003841; Na/Pi_transpt.
DR   InterPro; IPR004633; NaPi_cotrn-rel/YqeW-like.
DR   InterPro; IPR038078; PhoU-like_sf.
DR   InterPro; IPR026022; PhoU_dom.
DR   NCBIfam; NF037997; Na_Pi_symport; 1.
DR   NCBIfam; TIGR00704; NaPi_cotrn_rel; 1.
DR   PANTHER; PTHR10010:SF46; SODIUM_PHOSPHATE COTRANSPORTER-RELATED; 1.
DR   PANTHER; PTHR10010; SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED; 1.
DR   Pfam; PF02690; Na_Pi_cotrans; 2.
DR   Pfam; PF01895; PhoU; 2.
DR   SUPFAM; SSF109755; PhoU-like; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000195962};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        101..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        130..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        173..199
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        211..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        244..264
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        284..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          349..434
FT                   /note="PhoU"
FT                   /evidence="ECO:0000259|Pfam:PF01895"
FT   DOMAIN          453..536
FT                   /note="PhoU"
FT                   /evidence="ECO:0000259|Pfam:PF01895"
SQ   SEQUENCE   542 AA;  59309 MW;  790827347E525A48 CRC64;
     MGITDVLSLL GGLALFLYGM QMMSNGLEAA AGNKMKSILE KLTSNRIKGV LVGAAITAVI
     QSSSATTVMV VGFVNSGLMT LYQAVWIIMG ANIGTTITGQ LIALDIGAIA PLIAIISVAV
     MMFVKNEKAH HISSIFAGLG ILFMGMNMMG TAMEPLQDSE AFINLMTKFS NPLIGILVGA
     VFTAIIQSSS ASVGILQALA ATGMIPLSSA VYVLFGQNIG TCITAVLASI GMKVNAKRTT
     IIHLMFNIIG TIIFTVICMT TPYVSLVEAI SPGDPVRQIA NAHTIFNIVT TLILLPFGTQ
     MADLAVKILP DSKKEDDEDL RLKYIRPFES SYAIGHSAVA VSQVRDEVGR MRDMVCKNIS
     DAFDTLIKYD EKSRRKVAER EEYIDFLNKG ISEYVVSLMA SEMSTDDSRK INGYYAIISN
     LERIGDHAVN IAEYADDMKK WDLQFSDNVL EELEEMKKQC VQSLDNVKEV TSDNADRVLS
     QAVLLEQKTD DLRDKYFKKQ MQRLKKGKCK PQSGIVFSEI LTDFERMGDH ALNIAQEYQG
     MK
//