ID A0A1Y4S4Z4_9FIRM Unreviewed; 327 AA.
AC A0A1Y4S4Z4;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=HTH lacI-type domain-containing protein {ECO:0000259|PROSITE:PS50932};
GN ORFNames=B5E80_05555 {ECO:0000313|EMBL:OUQ24915.1};
OS Flavonifractor sp. An135.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Flavonifractor.
OX NCBI_TaxID=1965558 {ECO:0000313|EMBL:OUQ24915.1, ECO:0000313|Proteomes:UP000196472};
RN [1] {ECO:0000313|Proteomes:UP000196472}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An135 {ECO:0000313|Proteomes:UP000196472};
RA Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA Rychlik I.;
RT "Function of individual gut microbiota members based on whole genome
RT sequencing of pure cultures obtained from chicken caecum.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUQ24915.1}.
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DR EMBL; NFLG01000007; OUQ24915.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y4S4Z4; -.
DR OrthoDB; 3180992at2; -.
DR Proteomes; UP000196472; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd01542; PBP1_TreR-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR PANTHER; PTHR30146:SF134; OPERON REPRESSOR, PUTATIVE-RELATED; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000196472};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..54
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 327 AA; 35496 MW; DF1B7120DEE7F075 CRC64;
MTIKEIAQMA GVSSAAVSRY LNGGSLSQQK RDVIRDVIQR TGYRPDAAAQ MLRSKVTDYT
GVIVPKINSD AVSRVTAGIT QVLSQRGYLC LLANTSGEPE QELAYLELFQ DRSVAGIILM
ATVLPPRHQE MLKACTVPLV VAGQQCEGVP CVYHDDYNAA RELTGRLIQR GRRKLVYIGV
TEQDIAVGLH RKQGMRAALT EAGLSPDIPC AVSNFTADGG RRAMEELLQA HPDLDGVMCS
TDLIAIGAME ALRAAGKELP RDVSVAGIDD SWAGAHITPR LTTAHFYYEE CGAEAARMLL
SMVDQKDGDL PVRQTMMGYT VVERDSI
//
