ID A0A1Y4SA88_9FIRM Unreviewed; 580 AA.
AC A0A1Y4SA88;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Multidrug ABC transporter ATP-binding protein {ECO:0000313|EMBL:OUQ26769.1};
GN ORFNames=B5E80_00250 {ECO:0000313|EMBL:OUQ26769.1};
OS Flavonifractor sp. An135.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Flavonifractor.
OX NCBI_TaxID=1965558 {ECO:0000313|EMBL:OUQ26769.1, ECO:0000313|Proteomes:UP000196472};
RN [1] {ECO:0000313|Proteomes:UP000196472}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=An135 {ECO:0000313|Proteomes:UP000196472};
RA Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA Rychlik I.;
RT "Function of individual gut microbiota members based on whole genome
RT sequencing of pure cultures obtained from chicken caecum.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUQ26769.1}.
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DR EMBL; NFLG01000001; OUQ26769.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y4SA88; -.
DR OrthoDB; 9762778at2; -.
DR Proteomes; UP000196472; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd07346; ABC_6TM_exporters; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039421; Type_1_exporter.
DR PANTHER; PTHR24221:SF397; ABC TRANSPORTER, ATP-BINDING TRANSMEMBRANE PROTEIN; 1.
DR PANTHER; PTHR24221; ATP-BINDING CASSETTE SUB-FAMILY B; 1.
DR Pfam; PF00664; ABC_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:OUQ26769.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000196472};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 57..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 251..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..295
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 20..304
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 335..569
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 580 AA; 63974 MW; 0DB9B0CA16F84946 CRC64;
MLKIIRRVLR LSGNLSKRIW GSFICGFLES MFGLLPIAAV FLVLIELQNG QPITGQTWGI
VIGLIAGGLI LRMIFKYLVY RLQSTAGFEF VARERIALGD RLRNVPMGFF HDNSVGDITA
TVTTDLNFLE NYSMHILDKV TTGVLSMIVM AGCILAFDWR IGLIFVAGIL LSFPIYSHMQ
KKGKALSAKR QKIQSEAVAA TLEYVQGISV VKSFNMCDKN LSDIEDAYES NAAASYGVER
VFTPLNMTYS MVFRISACMI MLCAGILAVG GDLSFANLAV ILIASFTIFN PIEVMGQMTT
MIRTMDAALD RVERIKQAKK IDENGRDIPL DSFDIGFEHV SFAYENGNPI LKDVSFSIPQ
GSMTAIVGPS GGGKTTITRL IARFWDVQEG SITIGGHDVK EFTCDSLLKN MSMVFQNVYL
FHDTIENNIK FGCPDATHDQ VVEAAKKACC HDFISALPQG YDTVIGEGGS TLSGGEKQRI
SIARAMLKDA PIILLDEATA SVDPENEVHL QQAISALVKN KTLIVIAHRL STIRDADQIL
VVDNGKIVEK GVHAELIQQK GIYQKFWNIR QKARNWKLAQ
//
