ID   A0A1Y4SCS4_9FIRM        Unreviewed;       784 AA.
AC   A0A1Y4SCS4;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Helicase {ECO:0000313|EMBL:OUQ27668.1};
GN   ORFNames=B5E77_06150 {ECO:0000313|EMBL:OUQ27668.1};
OS   Lachnoclostridium sp. An131.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1965555 {ECO:0000313|EMBL:OUQ27668.1, ECO:0000313|Proteomes:UP000199743};
RN   [1] {ECO:0000313|Proteomes:UP000199743}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=An131 {ECO:0000313|Proteomes:UP000199743};
RA   Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA   Rychlik I.;
RT   "Function of individual gut microbiota members based on whole genome
RT   sequencing of pure cultures obtained from chicken caecum.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the helicase family. DinG subfamily.
CC       {ECO:0000256|ARBA:ARBA00038058}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUQ27668.1}.
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DR   EMBL; NFLI01000006; OUQ27668.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y4SCS4; -.
DR   OrthoDB; 9765586at2; -.
DR   Proteomes; UP000199743; Unassembled WGS sequence.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.275.40; -; 1.
DR   Gene3D; 3.90.320.10; -; 1.
DR   Gene3D; 1.10.30.20; Bacterial XPD DNA helicase, FeS cluster domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR006555; ATP-dep_Helicase_C.
DR   InterPro; IPR045028; DinG/Rad3-like.
DR   InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR   InterPro; IPR006554; Helicase-like_DEXD_c2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011604; PDDEXK-like_dom_sf.
DR   InterPro; IPR010614; RAD3-like_helicase_DEAD.
DR   InterPro; IPR042493; XPD_DNA_FeS.
DR   PANTHER; PTHR11472; DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; 1.
DR   PANTHER; PTHR11472:SF47; FANCONI ANEMIA GROUP J PROTEIN; 1.
DR   Pfam; PF06733; DEAD_2; 1.
DR   Pfam; PF13307; Helicase_C_2; 1.
DR   SMART; SM00488; DEXDc2; 1.
DR   SMART; SM00491; HELICc2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:OUQ27668.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199743}.
FT   DOMAIN          185..445
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51193"
SQ   SEQUENCE   784 AA;  89969 MW;  49C02C89117CE2A8 CRC64;
     MDEMRTEIRI SVRSLVEFIL REGDLDNRIT GKADPLAMQA GSRLHRKIQK RMGAGYAAEV
     PLKIKVPMGE FDCVVEGRAD GIFSEDGMSW IDEIKGVYRD LGLIEKPLGV HLAQALCYAF
     IYASQQELPE IGVQLTYGNL ETEELKAFRE TRTREELEEW FSGLLEEYRK WAGFQFEWKR
     TRKESIRPLE FPFPYREGQY DLAAGVYRTI ARKKRLFIQA PTGVGKTIST VFPAVKAVGE
     GLGDRIFYLT AKTVTRTVAE ETFRILREKG LRMKTVTLTA KEKLCICEEV QCNPEACPYA
     KGHFDRVNAA VFELLTEGPD ELSREVLLKQ AHKHQVCPFE LSLDTASWTD AVICDYNYVF
     DPGVRLKRFF AEGVKGEYLF LIDEAHNLVE RGREMFSASL CKEDFLELKR KVKGRYKKAE
     RCLERCNKYL LGLKKECDTY QLHEDVGAFV LQLLSLSTEL DRIREEGADP ELQKEVLDFW
     FQVRDFLNTA DRLDENYVIY SEIGEDGHFR LKLYCVETAK SLRECLDKGN AAIFFSATLL
     PMPYYKHLLG DENDYAVYAR SPFSAEKRLL LLGQDVSSRY TRRNRTEYER IADYLAAMTE
     GRKGNYLAFF PSYRMMQEVF EVFQDKYGGL AECAIQRSGM KEEEREAFLG QFEAGGRKSL
     LGFCVLGGIF SEGIDLKREA LIGAAVVGTG LPQVCHEREI LRQYYEEKGM DGFAYAYRYP
     GMNKVLQAAG RVIRTDEDRG VILLLDNRFL GSDYRGLFPL EWGDCQVCRL KDAGKRIGEF
     WEGI
//