ID   A0A1Y4T0H7_9FIRM        Unreviewed;       429 AA.
AC   A0A1Y4T0H7;
DT   30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2017, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   RecName: Full=Permease IIC component {ECO:0000256|PIRNR:PIRNR006351};
GN   ORFNames=B5E75_06730 {ECO:0000313|EMBL:OUQ34493.1};
OS   Massilimicrobiota timonensis.
OC   Bacteria; Bacillota; Erysipelotrichia; Erysipelotrichales;
OC   Erysipelotrichaceae; Massilimicrobiota.
OX   NCBI_TaxID=1776392 {ECO:0000313|EMBL:OUQ34493.1, ECO:0000313|Proteomes:UP000195305};
RN   [1] {ECO:0000313|Proteomes:UP000195305}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=An13 {ECO:0000313|Proteomes:UP000195305};
RA   Medvecky M., Cejkova D., Polansky O., Karasova D., Kubasova T., Cizek A.,
RA   Rychlik I.;
RT   "Function of individual gut microbiota members based on whole genome
RT   sequencing of pure cultures obtained from chicken caecum.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The phosphoenolpyruvate-dependent sugar phosphotransferase
CC       system (PTS), a major carbohydrate active -transport system, catalyzes
CC       the phosphorylation of incoming sugar substrates concomitant with their
CC       translocation across the cell membrane.
CC       {ECO:0000256|PIRNR:PIRNR006351}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUQ34493.1}.
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DR   EMBL; NFLJ01000016; OUQ34493.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Y4T0H7; -.
DR   OrthoDB; 1550290at2; -.
DR   Proteomes; UP000195305; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR   InterPro; IPR003352; PTS_EIIC.
DR   InterPro; IPR004501; PTS_EIIC_3.
DR   InterPro; IPR004796; PTS_IIC_cello.
DR   NCBIfam; TIGR00410; lacE; 1.
DR   PANTHER; PTHR33989; -; 1.
DR   PANTHER; PTHR33989:SF8; PERMEASE IIC COMPONENT; 1.
DR   Pfam; PF02378; PTS_EIIC; 1.
DR   PIRSF; PIRSF006351; PTS_EIIC-Cellobiose; 1.
DR   PROSITE; PS51105; PTS_EIIC_TYPE_3; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR006351};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR006351};
KW   Sugar transport {ECO:0000256|ARBA:ARBA00022597,
KW   ECO:0000256|PIRNR:PIRNR006351};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR006351}.
FT   TRANSMEM        35..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        76..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        103..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        143..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        182..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        221..245
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        252..273
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        279..307
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        342..369
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        389..414
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          11..411
FT                   /note="PTS EIIC type-3"
FT                   /evidence="ECO:0000259|PROSITE:PS51105"
SQ   SEQUENCE   429 AA;  46946 MW;  C86DA3EF7FC3F2FC CRC64;
     MNFFNKLQVG LEKIVGPFAT MVANSKYIKA LTEGFMYTMP ITLGVAVIAV LSNLPIDPWV
     DFLNSTGLYT VGQEVVSLTL SLLAIYVVGA IGYCFTRNEG EQGIIGAVMS TAAFIILMPI
     QTFTNEAGTS VSALSTSYMG SDGIFLALIL GLLIPRLYCY LMSKNLKLKL PDSVPPMVSM
     SLAPTFVAMI IFTFVFALKW ACTFTPYGNV FNVVSTLIGQ PISYFGASPI SLIIVFSLMN
     LIWFFGIHPN AILMPYMPVL MMASMANTEA FLAGETMPYL VFGILGACVQ IGGAGNTLGL
     CIATLFAKSE KYKAMRKLVI PANIFNINEP IIFGFPIMLN PLYVIPMVFS PAASGLVAWA
     LIGIFPIQFN PTISMPWVTP GFITTFFQGG IFMLLLWLIS LAIHFIMYLP FFLIDDNNAL
     KQEQEMKAQ
//